{"id":"W2077022750","doi":"10.1097/00024382-200014030-00029","title":"IN VIVO AND IN VITRO MODULATION OF INTERCELLULAR ADHESION MOLECULE (ICAM)-1 EXPRESSION BY HYPERTONICITY","year":2000,"lang":"en","type":"article","venue":"Shock","topic":"Organ Transplantation Techniques and Outcomes","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"In vivo; Umbilical vein; Intercellular Adhesion Molecule-1; Hypertonic saline; Lipopolysaccharide; Western blot; Cell adhesion molecule; Chemistry; ICAM-1; In vitro; Endothelial stem cell; Intracellular; Pharmacology; Andrology; Immunology; Internal medicine; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002551071,0.0004745588,0.0002902942,0.0001986772,0.0001564544,0.0002955612,0.0002175397,0.0002232186,0.001759906],"category_scores_gemma":[0.0001366972,0.0001636937,0.0003094967,0.0001654013,0.0002835293,0.0002568651,0.0001426165,0.0008470874,0.0003560796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003521971,"about_ca_system_score_gemma":0.0001706954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000523374,"about_ca_topic_score_gemma":0.0007138416,"domain_scores_codex":[0.9997342,0.00007230576,0.00002123281,0.00002908776,0.00004714597,0.00009599451],"domain_scores_gemma":[0.9998405,0.00004003324,0.00004094432,0.00002580543,0.00001526106,0.00003738515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000433358,0.000138795,0.0001007701,0.00003495962,0.000004589431,0.00003046985,0.0000123239,0.00006585004,0.9986099,0.00004762344,0.00004140431,0.0004798998],"study_design_scores_gemma":[0.00005619611,0.002302505,0.003226931,0.000005510021,0.00002885836,0.00009560018,0.00003002243,0.0006569123,0.9928939,0.00004048789,0.0006583551,0.000004632396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947536,0.001813223,0.001517785,0.0001327306,0.00005628139,0.00003457282,0.0002837023,0.00003230874,0.001375636],"genre_scores_gemma":[0.993672,0.001859654,0.001645305,0.00009487408,0.00007382103,0.00009299532,0.0007164214,0.00001509072,0.001829825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001759906,"threshold_uncertainty_score":0.005887508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00787382640688303,"score_gpt":0.2478435621230966,"score_spread":0.2399697357162136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}