{"id":"W2077047516","doi":"10.1371/journal.pone.0044872","title":"Systematic Differences in Signal Emitting and Receiving Revealed by PageRank Analysis of a Human Protein Interactome","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of New Brunswick","funders":"","keywords":"Interactome; PageRank; Ranking (information retrieval); Computational biology; Rank (graph theory); Biology; Function (biology); Computer science; Protein subunit; Bioinformatics; Genetics; Information retrieval; Gene; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004665338,0.0001955835,0.0002772157,0.002814186,0.0003121239,0.0004511966,0.0001164733,0.0001972862,0.0008682557],"category_scores_gemma":[0.002174147,0.0001067168,0.0002599948,0.001618032,0.0003328825,0.0004786594,0.0002398339,0.0001764202,0.0003059597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001721869,"about_ca_system_score_gemma":0.0001664687,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005954198,"about_ca_topic_score_gemma":0.0008147776,"domain_scores_codex":[0.9995986,0.00009446288,0.00003448272,0.0001145654,0.000105867,0.000052149],"domain_scores_gemma":[0.9984196,0.0006785151,0.0004503009,0.0001400191,0.0001898773,0.0001217168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001740963,0.0001336665,0.4553751,0.0005121466,0.0004928074,0.0008799311,0.001128516,0.006646805,0.4503668,0.003754063,0.001473368,0.0774959],"study_design_scores_gemma":[0.00002282658,0.0002384075,0.9168075,0.00001898549,0.0002243165,0.00142346,0.0004572501,0.03388199,0.03954567,0.004698877,0.002630107,0.00005065182],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940439,0.0003137004,0.004398202,0.00003744317,0.000003698515,0.000008049592,0.0005148753,0.0001061317,0.0005740635],"genre_scores_gemma":[0.9949981,0.0001135767,0.003480829,0.00001028079,0.000008105991,0.000008420878,0.001111071,0.00001738114,0.000252341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002814186,"threshold_uncertainty_score":0.002904594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01945481229573823,"score_gpt":0.2227424633134627,"score_spread":0.2032876510177245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}