{"id":"W2077171860","doi":"10.1007/s00018-007-7228-2","title":"Leukotrienes: Mediators that have been typecast as villains","year":2007,"lang":"en","type":"review","venue":"Cellular and Molecular Life Sciences","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Immune system; Innate immune system; Immunology; Inflammation; Biology; Lipid signaling; Immunity; Receptor; Pattern recognition receptor; Neuroscience; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000530247,0.0004789056,0.001267194,0.0004417488,0.0002898437,0.00007039658,0.0003079293,0.0003626934,0.0001209214],"category_scores_gemma":[0.0002313809,0.0003215017,0.0005290351,0.0004993959,0.0009599546,0.00007096497,0.0001473365,0.0002893966,0.0001187333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000460433,"about_ca_system_score_gemma":0.00150576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001494045,"about_ca_topic_score_gemma":0.000002258832,"domain_scores_codex":[0.9973479,0.0001205189,0.0004363839,0.0007708273,0.0008083726,0.0005160292],"domain_scores_gemma":[0.9984128,0.00009251695,0.0002292118,0.0003729568,0.00006377356,0.0008287003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002186856,0.0001482436,0.0004260309,0.008640306,0.0002520384,0.002496894,0.0001492803,7.338334e-7,0.00007668639,0.0008987446,0.001367275,0.9855219],"study_design_scores_gemma":[0.0002350847,0.0002444043,0.000007834479,0.002345629,0.0007925021,0.0001218722,0.0004338466,0.000004296603,0.0002774482,0.00002155461,0.9951352,0.0003803159],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009112362,0.9862484,0.0002340414,0.00004728488,0.0003047738,0.0006254698,0.00001625292,0.00005322973,0.01155927],"genre_scores_gemma":[0.002208701,0.9958073,0.0001051878,0.000861396,0.0003365714,0.00002119155,0.00005966156,0.00004989986,0.0005501163],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9937679,"threshold_uncertainty_score":0.9999237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05337770283402857,"score_gpt":0.3449999559664284,"score_spread":0.2916222531323998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}