{"id":"W2077235837","doi":"10.1016/j.artres.2008.08.309","title":"P1.01 TREATMENT WITH DEXAMETHASONE REVERSES IMPARED ELASTOGENESIS AND COLLAGENOGENESIS IN CULTURES OF FIBROBLASTS FROM PATIENTS WITH LOEYS-DIETZ SYNDROME (LDS)","year":2008,"lang":"en","type":"article","venue":"Artery Research","topic":"Genetic Syndromes and Imprinting","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Dexamethasone; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002938907,0.0004395468,0.0006514535,0.0004003702,0.0003406948,0.0005016169,0.0005377695,0.0006092077,0.004995096],"category_scores_gemma":[0.0007404308,0.000214659,0.000411257,0.0003170575,0.0007086678,0.0002787779,0.0002977756,0.001453463,0.0007792907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000239479,"about_ca_system_score_gemma":0.0005689792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002466313,"about_ca_topic_score_gemma":0.0032624,"domain_scores_codex":[0.9995593,0.0001046499,0.00005824264,0.00008303993,0.00005927322,0.0001354319],"domain_scores_gemma":[0.9991996,0.000349513,0.00005025133,0.0001099857,0.0000485512,0.0002421368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005232903,0.0004111118,0.0009795112,0.000115467,0.00003312193,0.001703049,0.0001649555,0.00005751435,0.9863219,0.0002769217,0.0003363402,0.004367127],"study_design_scores_gemma":[0.0005937177,0.003662835,0.01313043,0.00002578144,0.00006690513,0.002637692,0.000451961,0.0004930334,0.9734084,0.0001589446,0.005354062,0.00001610399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915496,0.003326437,0.0008529112,0.0004164701,0.0005403221,0.00003937598,0.0006258125,0.00008338574,0.002565701],"genre_scores_gemma":[0.9933983,0.001124761,0.0008678582,0.0001091524,0.000113885,0.00004681212,0.000813171,0.00002538637,0.003500699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004995096,"threshold_uncertainty_score":0.01671028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02711041844936865,"score_gpt":0.2762683297107883,"score_spread":0.2491579112614196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}