{"id":"W2077302783","doi":"10.1111/j.1474-9726.2007.00288.x","title":"Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts","year":2007,"lang":"en","type":"article","venue":"Aging Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Cancer Institute; National Institute on Aging; National Institutes of Health","keywords":"Telomerase; Telomere; Dyskeratosis congenita; Biology; Telomerase reverse transcriptase; Telomerase RNA component; Cell biology; Somatic cell; Stem cell; Cancer research; Senescence; Haematopoiesis; Molecular biology; Genetics; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001785637,0.0002328073,0.0001430801,0.0002161427,0.0001427202,0.0002280792,0.0001502131,0.0002022299,0.0008101892],"category_scores_gemma":[0.0001116481,0.00008992373,0.0001287975,0.00008477514,0.0001237967,0.00009087429,0.0001199219,0.0003386791,0.0002055418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001458014,"about_ca_system_score_gemma":0.0001365084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003002809,"about_ca_topic_score_gemma":0.0005006422,"domain_scores_codex":[0.9999092,0.00001499052,0.00001479342,0.00002113135,0.0000253508,0.0000145904],"domain_scores_gemma":[0.9998919,0.00002510468,0.00002554295,0.00002198017,0.00001049063,0.00002499307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000530626,0.00003637043,0.0001479908,0.00002353334,0.000002097562,0.0001057234,0.00001916313,0.00006759048,0.9979039,0.0001269831,0.00003059066,0.001483007],"study_design_scores_gemma":[0.00004618939,0.0005975981,0.004223796,0.00001087931,0.0000220371,0.001024543,0.0000400898,0.001010078,0.9875517,0.0000959211,0.005370966,0.000006204905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953051,0.0009391978,0.001512595,0.00004371565,0.00002503424,0.00002401042,0.0002182714,0.00007340171,0.001858713],"genre_scores_gemma":[0.9948556,0.0006113953,0.001404384,0.0000249092,0.000009105512,0.00002835267,0.0002689416,0.00001378198,0.002783506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008101892,"threshold_uncertainty_score":0.002710283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01339370191324715,"score_gpt":0.2685501806266029,"score_spread":0.2551564787133558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}