{"id":"W2077309151","doi":"10.4161/19336934.2014.969147","title":"“Ready, Set, Go”: Checkpoint regulation by Cdk1 inhibitory phosphorylation","year":2014,"lang":"en","type":"article","venue":"Fly","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Directorate for Biological Sciences","keywords":"Cyclin-dependent kinase 1; Cell biology; Phosphorylation; G2-M DNA damage checkpoint; Wee1; Biology; CHEK1; Mitosis; Kinase; Phosphorylation cascade; Cell cycle checkpoint; Cdc25; Cell cycle; Protein phosphorylation; Genetics; Protein kinase A; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001530835,0.0001133346,0.00008698018,0.00001925525,0.00006194664,0.00001901965,0.00008526913,0.0001631752,0.00003196187],"category_scores_gemma":[0.00003163053,0.0001161604,0.00005283558,0.00003943543,0.0000328986,0.000004504072,0.00004423044,0.00006022964,0.00008598728],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001785461,"about_ca_system_score_gemma":0.00002229127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002452648,"about_ca_topic_score_gemma":0.00002397863,"domain_scores_codex":[0.9993079,0.00003840516,0.0001643929,0.000249397,0.00008524071,0.0001546225],"domain_scores_gemma":[0.999548,0.000005114613,0.00007365734,0.0002673164,0.00005376285,0.0000521024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002102104,0.00002213237,0.0004684421,0.000008599885,0.00001167914,9.716095e-8,0.00003491763,0.00003506478,0.9485611,0.0001808093,0.04633707,0.004319019],"study_design_scores_gemma":[0.0003080355,0.0001015744,0.001655456,0.000007436898,0.00001049135,0.00000320898,0.00001403513,0.000838528,0.6329173,0.0001319031,0.3638586,0.0001535085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9746215,0.0004136505,0.0169568,0.0001358956,0.0002765018,0.0001582759,0.00002676238,0.00002892989,0.00738166],"genre_scores_gemma":[0.9926884,0.00005748384,0.0004545376,0.0003355991,0.0003690006,0.00001257645,0.001065237,0.00002233467,0.004994804],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3175215,"threshold_uncertainty_score":0.4736885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005443168533946735,"score_gpt":0.2143888770003384,"score_spread":0.2089457084663917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}