{"id":"W2077356175","doi":"10.1038/jcbfm.2009.227","title":"Early Ischemia Enhances Action Potential-Dependent, Spontaneous Glutamatergic Responses in CA1 Neurons","year":2009,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Alzheimer Society; Heart and Stroke Foundation of Canada","keywords":"Glutamate receptor; Glutamatergic; Excitatory postsynaptic potential; Neuroscience; Excitotoxicity; NMDA receptor; Hippocampal formation; Ischemia; Neurotransmitter; Inhibitory postsynaptic potential; Neurotransmission; Electrophysiology; Chemistry; Biology; Biophysics; Central nervous system; Receptor; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001478534,0.0004781473,0.0004227702,0.0001481758,0.0000987776,0.0002402344,0.0001867972,0.0002285226,0.001144833],"category_scores_gemma":[0.0002485508,0.0001339375,0.0002657789,0.0001165785,0.0001689763,0.0003218131,0.0002600803,0.0005336735,0.0001886918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003917084,"about_ca_system_score_gemma":0.000268963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008309786,"about_ca_topic_score_gemma":0.001626116,"domain_scores_codex":[0.9999104,0.000007086568,0.0000092129,0.00001467572,0.00001749218,0.00004112218],"domain_scores_gemma":[0.9998842,0.0000179082,0.00002994596,0.00001328441,0.00001280501,0.00004183493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005122439,0.00005712979,0.0003514865,0.0000858583,0.00001125516,0.0001152321,0.00003113184,0.00005611624,0.9964204,0.00004315427,0.00005876822,0.002257287],"study_design_scores_gemma":[0.000118994,0.00333667,0.07773095,0.00003156004,0.00007597037,0.0006138281,0.000104058,0.001260954,0.9153584,0.0002166518,0.001134445,0.00001758385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996937,0.001740493,0.0005594069,0.00005038661,0.00001879835,0.00001169802,0.0001265991,0.00004785773,0.0005077664],"genre_scores_gemma":[0.9972332,0.001038984,0.0005871805,0.00003836318,0.00002119084,0.00003025553,0.0002147316,0.000009804451,0.0008263805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001144833,"threshold_uncertainty_score":0.003829837,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02791844264540036,"score_gpt":0.3146358092501446,"score_spread":0.2867173666047442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}