{"id":"W2077361634","doi":"10.1126/science.1140114","title":"Combinatorial ShcA Docking Interactions Support Diversity in Tissue Morphogenesis","year":2007,"lang":"en","type":"article","venue":"Science","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Docking (animal); Signal transducing adaptor protein; SH2 domain; Phosphotyrosine-binding domain; Biology; Cell biology; GRB2; Tyrosine; Proto-oncogene tyrosine-protein kinase Src; Phosphorylation; Biochemistry; Chemistry; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001845814,0.0001230095,0.0001086686,0.0002973069,0.0001872949,0.0002897815,0.000146309,0.0001929913,0.001046127],"category_scores_gemma":[0.000249976,0.0001018702,0.00009833524,0.0001033626,0.0002187487,0.000184924,0.000408622,0.0002524109,0.0001579701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00018626,"about_ca_system_score_gemma":0.0001166668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001090391,"about_ca_topic_score_gemma":0.0004058014,"domain_scores_codex":[0.9998683,0.0000182949,0.000008339225,0.00002846207,0.00003673723,0.00003985234],"domain_scores_gemma":[0.9997694,0.00003893928,0.00005258219,0.00002730903,0.00002114763,0.00009066035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000102181,0.00001086751,0.004657447,0.00001176462,0.000008019066,0.0001000507,0.00001975297,0.00009110764,0.9922122,0.0003588609,0.00003560396,0.002392227],"study_design_scores_gemma":[0.00006937046,0.0004485317,0.2777452,0.00001633519,0.00006362823,0.002048664,0.0002542775,0.003609973,0.7109843,0.001082573,0.003662038,0.00001511476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984899,0.000191173,0.0005123439,0.00001829625,0.000003477856,0.000002324192,0.0000179923,0.000009825572,0.0007546629],"genre_scores_gemma":[0.9992772,0.00006841409,0.0003059744,0.00001066428,0.000003337951,0.000003265027,0.00003991263,0.000002505714,0.0002887123],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001046127,"threshold_uncertainty_score":0.003499627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03555263222108038,"score_gpt":0.3428838917392453,"score_spread":0.3073312595181649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}