{"id":"W2077488231","doi":"10.1080/10428190701799035","title":"Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia","year":2008,"lang":"en","type":"article","venue":"Leukemia & lymphoma/Leukemia and lymphoma","topic":"Toxin Mechanisms and Immunotoxins","field":"Immunology and Microbiology","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute","keywords":"Medicine; Chills; Diphtheria toxin; Refractory (planetary science); Myeloid leukemia; Gastroenterology; Internal medicine; Hypoalbuminemia; Diphtheria; Leukemia; Surgery; Immunology; Vaccination; Toxin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008685804,0.0009235233,0.001297023,0.0002265067,0.000325264,0.0005701385,0.0004549534,0.000762534,0.001095483],"category_scores_gemma":[0.0005973729,0.0003319963,0.0006492711,0.000302952,0.00073201,0.0004539865,0.0002485875,0.002048391,0.0004123362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007044812,"about_ca_system_score_gemma":0.0009534268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006168978,"about_ca_topic_score_gemma":0.001029796,"domain_scores_codex":[0.9997405,0.000118485,0.00001100168,0.0000359453,0.00002385973,0.00007027708],"domain_scores_gemma":[0.9996284,0.00006889562,0.00007279722,0.00002792862,0.00002090235,0.0001810314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4713972,0.1013589,0.01883772,0.0008492309,0.001168612,0.001063299,0.001034301,0.005533664,0.1689882,0.0009251398,0.006021136,0.2228225],"study_design_scores_gemma":[0.2830077,0.6811028,0.01776325,0.00003800826,0.0003611533,0.0007210103,0.00009213147,0.001698284,0.009724882,0.0003523451,0.005114741,0.00002371907],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944171,0.001836626,0.0006415086,0.0003466103,0.00007087392,0.001173006,0.0002185495,0.00007142258,0.001224315],"genre_scores_gemma":[0.9950725,0.001019404,0.001034062,0.0004323861,0.00006811882,0.001106165,0.0005561223,0.00001545663,0.0006957894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297023,"threshold_uncertainty_score":0.005111396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033369051243744,"score_gpt":0.2437671816726062,"score_spread":0.2334334911601688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}