{"id":"W2077531012","doi":"10.1053/jhep.2001.23077","title":"Resistance to Fulminant Hepatitis and Carcinogenesis Conferred by Overexpression of Retinoblastoma Protein in Mouse Liver","year":2001,"lang":"en","type":"article","venue":"Hepatology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"","keywords":"Carcinogenesis; Transgene; Genetically modified mouse; Biology; Retinoblastoma; Cancer research; HBx; Gene; Hepatocyte; Enhancer; Hepatocyte nuclear factor 4; Molecular biology; Transfection; Gene expression; Transcription factor; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000307047,0.0004521061,0.0002732143,0.0004826153,0.0001313586,0.0002829684,0.0001550002,0.0003861646,0.000790778],"category_scores_gemma":[0.0002058125,0.0002270719,0.0002309546,0.0001459111,0.0002790566,0.0002353826,0.0001987692,0.0006125849,0.0004102515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001981727,"about_ca_system_score_gemma":0.0001180562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001685912,"about_ca_topic_score_gemma":0.0002086808,"domain_scores_codex":[0.9997819,0.00005480118,0.00002355783,0.00004021567,0.00004519225,0.00005433096],"domain_scores_gemma":[0.9997459,0.00004007529,0.00009463452,0.00004678909,0.00001524365,0.00005734884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007440107,0.00001216874,0.00009694423,0.00000921032,0.000002090071,0.00004138635,0.00001015239,0.00002745085,0.9991072,0.0000902383,0.00001084311,0.0005177869],"study_design_scores_gemma":[0.00004035724,0.0006167919,0.001551682,0.000005569143,0.00001692081,0.0005999873,0.00001330351,0.0004700632,0.9949859,0.00009381471,0.00160082,0.000004641886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934302,0.001140301,0.00398504,0.0001230929,0.00001713326,0.00002129099,0.0001196368,0.0002305817,0.0009327357],"genre_scores_gemma":[0.9938332,0.0008415272,0.002390255,0.00003119388,0.0000123341,0.00002983942,0.0002645873,0.00003917705,0.002557813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000790778,"threshold_uncertainty_score":0.002645433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009199315240414799,"score_gpt":0.2236094122850514,"score_spread":0.2144100970446365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}