{"id":"W2077533945","doi":"10.1038/sj.pcan.4500852","title":"Effects of geldanamycin on HIF-1α mediated angiogenesis and invasion in prostate cancer cells","year":2006,"lang":"en","type":"article","venue":"Prostate Cancer and Prostatic Diseases","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Geldanamycin; Angiogenesis; Prostate cancer; Medicine; Cancer research; Benign prostatic hyperplasia (BPH); Oncology; Cancer; Hsp90; Internal medicine; Biology; Heat shock protein; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009385136,0.0002856973,0.0003595233,0.0001173576,0.00007271974,0.00003473393,0.00008003135,0.00007496482,0.00001253114],"category_scores_gemma":[0.000048737,0.0002494582,0.00006561587,0.0002118143,0.000181639,0.00001632408,0.00007185993,0.00006617334,9.010312e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000268576,"about_ca_system_score_gemma":0.0002051498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001695311,"about_ca_topic_score_gemma":0.0006691916,"domain_scores_codex":[0.9984907,0.00007519278,0.0003342606,0.0005367535,0.0001935025,0.0003695753],"domain_scores_gemma":[0.9993407,0.00007168763,0.000154939,0.0001833871,0.00008743912,0.0001618871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001903637,0.0003873507,0.1066317,0.002242523,0.0001135467,0.00001754596,0.0006069815,0.000320647,0.831795,0.00005314078,0.003875276,0.05205274],"study_design_scores_gemma":[0.005313644,0.0005426047,0.2968392,0.0005432529,0.0002756511,0.000003153052,0.0001382097,0.00009132319,0.6776857,0.0005678182,0.01733937,0.0006599783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8998834,0.09764577,0.000004053874,0.0001541095,0.0003219689,0.001006119,0.0009268255,0.00001370109,0.00004399379],"genre_scores_gemma":[0.9432845,0.05483212,0.00005519241,0.0003044782,0.0002371336,0.0005802453,0.0002014155,0.00004238162,0.0004625392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1902076,"threshold_uncertainty_score":0.9999958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003789629419998366,"score_gpt":0.2235043331050639,"score_spread":0.2197147036850655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}