{"id":"W2077629365","doi":"10.1074/jbc.m011710200","title":"Molecular Characterization of Peripherin-2 and Rom-1 Mutants Responsible for Digenic Retinitis Pigmentosa","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Eye Institute","keywords":"Retinitis pigmentosa; Peripherin; Mutant; Genetics; Biology; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417486,0.000124028,0.0002200974,0.00001429137,0.00003223598,0.0000133753,0.0001552803,0.0001761727,0.00003956631],"category_scores_gemma":[0.0004801002,0.00009987619,0.00011017,0.00006178329,0.0001052211,0.000006107993,0.00007433109,0.00007583645,2.137527e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001085723,"about_ca_system_score_gemma":0.00006480627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.807588e-7,"about_ca_topic_score_gemma":1.632083e-7,"domain_scores_codex":[0.9991643,0.00003622977,0.0003700697,0.0001731326,0.0000960968,0.0001601167],"domain_scores_gemma":[0.9992254,0.00002384101,0.0003557823,0.0001453258,0.0001624187,0.00008727769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007937618,0.00005700822,0.002441,0.00003441092,0.00004093014,0.00001931674,0.000005353383,0.00000152118,0.9949512,0.00002287199,0.00002430915,0.001608317],"study_design_scores_gemma":[0.0006303918,0.0005844641,0.007909681,0.00003692423,0.00001827688,0.0002620242,0.00001800781,0.000004440804,0.985577,0.0001329391,0.004713088,0.0001127784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951768,0.002987039,0.00139972,0.0001272652,0.0000354865,0.0001142249,0.0000880483,0.000003469311,0.0000679315],"genre_scores_gemma":[0.9968854,0.001451111,0.00125545,0.00006981853,0.000142774,0.000008068815,0.0001138006,0.00001041198,0.00006311698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009374216,"threshold_uncertainty_score":0.4072833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01516500050141598,"score_gpt":0.2538400350956085,"score_spread":0.2386750345941926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}