{"id":"W2077662115","doi":"10.1371/journal.pone.0065991","title":"Persistence of the Oral Probiotic Streptococcus salivarius M18 Is Dose Dependent and Megaplasmid Transfer Can Augment Their Bacteriocin Production and Adhesion Characteristics","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Lawson Health Research Institute; University of Otago","keywords":"Probiotic; Streptococcus salivarius; Bacteriocin; Microbiology; Biology; Lactobacillus salivarius; Antimicrobial; Streptococcus pyogenes; Saliva; Plasmid; Streptococcus; Bacteria; Gene; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001827558,0.0002162164,0.000362261,0.0001503116,0.00008729439,0.0001949359,0.0001074384,0.0001820299,0.001069005],"category_scores_gemma":[0.0002069072,0.0001243777,0.0002132469,0.0001142832,0.0001326055,0.00009463591,0.0001906706,0.0002716791,0.0001433628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007783109,"about_ca_system_score_gemma":0.000106334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003633195,"about_ca_topic_score_gemma":0.0005201441,"domain_scores_codex":[0.9998399,0.00004068382,0.0000134074,0.00002694046,0.00003582126,0.00004316639],"domain_scores_gemma":[0.9999137,0.00001680591,0.00002572515,0.000008999531,0.00001108947,0.00002364516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002082886,0.0004069167,0.00542539,0.00005585873,0.00002794662,0.00005418647,0.00007459406,0.00004365151,0.9827806,0.00001592027,0.00005024436,0.008981789],"study_design_scores_gemma":[0.0001991935,0.05516113,0.2709731,0.00004889413,0.0002894621,0.0007219206,0.0003364912,0.0009998092,0.6676247,0.00006360064,0.00356028,0.00002153063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996161,0.0001753815,0.00007720978,0.000009569778,0.000002957885,0.000005509723,0.00002210955,0.00000347787,0.00008763838],"genre_scores_gemma":[0.9986664,0.0001948014,0.000271649,0.00002066154,0.000006084755,0.0000188757,0.00009772929,0.000003558618,0.0007202427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001069005,"threshold_uncertainty_score":0.003576219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04918933551539956,"score_gpt":0.2305658900401476,"score_spread":0.181376554524748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}