{"id":"W2077680424","doi":"10.1002/jcb.22373","title":"High‐pressure freezing of spermiogenic nuclei supports a dynamic chromatin model for the histone‐to‐protamine transition","year":2009,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Insect and Arachnid Ecology and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of British Columbia","funders":"","keywords":"Protamine; Spermatid; Sperm; Chromatin; Histone; Prophase; Biophysics; Biology; Cell biology; Chemistry; Spermiogenesis; Transmission electron microscopy; Biochemistry; Materials science; Nanotechnology; Genetics; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001004945,0.0001503025,0.00005960232,0.0001524914,0.0001884478,0.0001742249,0.0002965271,0.0001557545,0.0007711605],"category_scores_gemma":[0.0001280261,0.00009655637,0.0001599048,0.00006875251,0.0004066283,0.000342762,0.0001258118,0.0002151803,0.0001408551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002315963,"about_ca_system_score_gemma":0.0001274722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001240549,"about_ca_topic_score_gemma":0.002239056,"domain_scores_codex":[0.9999727,0.000002766555,0.000001626656,0.000007730339,0.00001014076,0.000004946818],"domain_scores_gemma":[0.999896,0.00003792962,0.00002195621,0.00001838917,0.00001749772,0.000008165143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003646632,0.000004413412,0.001090139,0.00004472057,0.000006493839,0.0001485819,0.00005513476,0.0005612344,0.9950083,0.001150728,0.00002657101,0.001867292],"study_design_scores_gemma":[0.0000166169,0.0001852056,0.03585854,0.00002469855,0.00002716043,0.0009710244,0.0001137098,0.009011432,0.9477898,0.001679053,0.00430628,0.00001656101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9436761,0.00127469,0.05006976,0.0001253169,0.0000468181,0.0000312445,0.0001708393,0.00007593315,0.004529357],"genre_scores_gemma":[0.9927516,0.0003867489,0.006073622,0.00002072444,0.00001142333,0.000009000511,0.0001666977,0.00001204243,0.0005681112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001240549,"threshold_uncertainty_score":0.002579808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005533836835311784,"score_gpt":0.2420437196011565,"score_spread":0.2365098827658448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}