{"id":"W2077692929","doi":"10.1016/j.tcm.2010.03.006","title":"Adenosine-Triphosphate-Binding Cassette Transporter-1 Trafficking and Function","year":2010,"lang":"en","type":"review","venue":"Trends in Cardiovascular Medicine","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Killam Trusts; Canada Research Chairs","keywords":"ABCA1; Tangier disease; ATP-binding cassette transporter; Adenosine triphosphate; Transporter; ATP Binding Cassette Transporter 1; Cell biology; Biogenesis; Biology; Efflux; Function (biology); Cholesterol; Lipoprotein; Adenosine; Reverse cholesterol transport; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001788207,0.0009310575,0.006197755,0.001748103,0.00009156923,0.00002460363,0.0001926567,0.0009835043,0.0002168398],"category_scores_gemma":[0.00007380827,0.0006761773,0.001953925,0.001428453,0.0002676489,0.0001210587,0.00004227599,0.002238583,0.00001854472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001339095,"about_ca_system_score_gemma":0.0001216134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001003845,"about_ca_topic_score_gemma":0.00003886578,"domain_scores_codex":[0.9956846,0.0002091064,0.001304072,0.001156537,0.0009896917,0.0006560438],"domain_scores_gemma":[0.9979219,0.0001084675,0.0002755073,0.001219122,0.0000659288,0.0004091193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003903184,0.00005191987,0.00007180408,0.00644163,0.001448375,0.0005812328,0.0002111257,0.00000103412,0.000006736322,0.0000183722,0.0002790294,0.9908497],"study_design_scores_gemma":[0.004347526,0.0001746873,0.002709699,0.01905413,0.02059726,0.001947056,0.0000454667,0.000004091149,0.000001820794,0.000002383308,0.9506161,0.0004997462],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0006703027,0.9942888,0.00006956259,0.0001801784,0.002130551,0.0006835065,0.00002339806,0.0001401894,0.001813491],"genre_scores_gemma":[0.001151703,0.9936821,0.00008187477,0.0001261824,0.002994742,0.0001156062,0.0007886628,0.0001732533,0.0008858397],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9903499,"threshold_uncertainty_score":0.9995689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04781974933966592,"score_gpt":0.3226111103542367,"score_spread":0.2747913610145707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}