{"id":"W2077707990","doi":"10.1016/j.chemphyslip.2010.05.116","title":"Inhibition of fatty acid synthase by the acyl-CoA hexanoate: a transcriptional effect","year":2010,"lang":"en","type":"article","venue":"Chemistry and Physics of Lipids","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"Eusko Jaurlaritza","keywords":"Chemistry; Fatty acid synthase; Biochemistry; Fatty acid; Acyl-CoA; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001235408,0.0001468391,0.0001587404,0.000003063598,0.00005771994,0.00000938807,0.0001147694,0.0001788713,0.00003640433],"category_scores_gemma":[0.00004037588,0.0001136371,0.00009407989,0.00006137433,0.0002895498,0.000007937872,0.00003963391,0.0002009601,5.890526e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003074416,"about_ca_system_score_gemma":0.0000371986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002898897,"about_ca_topic_score_gemma":2.898666e-7,"domain_scores_codex":[0.999365,0.00002633418,0.0001632726,0.0002044097,0.0001159945,0.0001250419],"domain_scores_gemma":[0.9995187,0.00002254748,0.0001000453,0.0002354083,0.00006567684,0.00005760111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001265047,0.00009888692,0.0008251664,0.0001767265,0.00005202019,1.047899e-7,0.00004005285,0.000001620218,0.9966184,0.00001722286,0.0002870501,0.00175628],"study_design_scores_gemma":[0.0004975274,0.00007807709,0.00007104135,0.00001948231,0.00002226406,0.000006443886,0.0000188021,0.00001242184,0.9978471,0.00007365549,0.001236735,0.0001164465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986566,0.0002086694,0.0003188597,0.00005851995,0.00009009638,0.00009041101,0.0001778617,0.00000611175,0.0003928895],"genre_scores_gemma":[0.9991708,0.00004209043,0.00009037731,0.00002534652,0.0003388588,0.00002009646,0.0002443518,0.00001305237,0.000054999],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001639834,"threshold_uncertainty_score":0.4633986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004872306295291946,"score_gpt":0.221064457122725,"score_spread":0.216192150827433,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}