{"id":"W2077715915","doi":"10.1038/nature14216","title":"MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection","year":2015,"lang":"en","type":"article","venue":"Nature","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":309,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Telomere; Genome instability; DNA repair; DNA damage; Biology; Non-homologous end joining; Cell biology; Homologous recombination; DNA; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002716689,0.0001514479,0.0001351254,0.00003213302,0.00007998607,0.00002501569,0.00008469261,0.00109707,0.00001388147],"category_scores_gemma":[0.0002971943,0.0001396991,0.00006614203,0.00006307157,0.00004894485,0.000006404136,0.0001623436,0.0004561691,0.000007569231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003773116,"about_ca_system_score_gemma":0.00002930034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001250224,"about_ca_topic_score_gemma":0.00007562548,"domain_scores_codex":[0.9989685,0.00006793634,0.0001411988,0.0003995504,0.0001950161,0.0002278026],"domain_scores_gemma":[0.9994398,0.0000145785,0.00007423493,0.0002327585,0.0001035279,0.0001351301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001764727,0.000017398,0.000424002,0.00001260891,0.00003328945,0.000006621967,0.00003196931,7.735819e-7,0.9285778,0.00007009826,0.06990559,0.0007434],"study_design_scores_gemma":[0.0008581608,0.0002581502,0.0002159011,0.00001426628,0.00001511169,0.00008107188,0.00008061179,0.00003924557,0.866441,0.000168169,0.1316682,0.0001600729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893942,0.005387047,0.00002293965,0.0003562046,0.0002352413,0.0001885145,0.00004676809,0.00006995638,0.004299077],"genre_scores_gemma":[0.9946764,0.00005016688,0.0004159481,0.0008860105,0.0003074792,0.00001575904,0.000169812,0.00002702011,0.003451386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06213674,"threshold_uncertainty_score":0.8461609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006249144784415382,"score_gpt":0.2399252899976755,"score_spread":0.2336761452132601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}