{"id":"W2077723816","doi":"10.1093/nar/gkv210","title":"Identification of recurrent regulated alternative splicing events across human solid tumors","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Planning and Budgeting Committee of the Council for Higher Education of Israel; Israeli Centers for Research Excellence; Azrieli Foundation; Israel Science Foundation","keywords":"Biology; RNA splicing; Alternative splicing; Exon; Computational biology; Cancer; Gene; Genetics; Cancer research; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002179499,0.0001464965,0.0002825034,0.0006381253,0.0001786833,0.0002978869,0.0001365195,0.0001955993,0.0006492646],"category_scores_gemma":[0.0004339292,0.0001336701,0.0002584141,0.0005658155,0.0001972386,0.00009162925,0.0002302624,0.0001831876,0.00025283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001484929,"about_ca_system_score_gemma":0.0001191935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003691085,"about_ca_topic_score_gemma":0.001030087,"domain_scores_codex":[0.9997309,0.00002279027,0.00002296895,0.0001077126,0.00008464399,0.00003104029],"domain_scores_gemma":[0.9996397,0.00008506094,0.0001287331,0.00005704189,0.00005112076,0.00003831917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002627837,0.00001798162,0.04756844,0.00007980548,0.0001149277,0.000602378,0.000114665,0.0003819242,0.9414269,0.0001243009,0.0001165446,0.009189278],"study_design_scores_gemma":[0.00002906998,0.000335808,0.7232866,0.00002053647,0.000298747,0.007388362,0.0001808681,0.004945706,0.2578345,0.0007228848,0.004926927,0.00002992947],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958093,0.0006124506,0.002396901,0.00001734074,0.000005109984,0.00001218971,0.0007554549,0.00005536976,0.0003358948],"genre_scores_gemma":[0.9958146,0.0002092244,0.002055357,0.00002789598,0.000005381741,0.00001410088,0.001494999,0.00002111536,0.0003573737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006492646,"threshold_uncertainty_score":0.002172053,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06980085232031173,"score_gpt":0.4251967745007812,"score_spread":0.3553959221804694,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}