{"id":"W2077724030","doi":"10.1126/scisignal.2002258","title":"miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast CancerA presentation from the Keystone Symposium on Epithelial Plasticity and Epithelial to Mesenchymal Transition, Vancouver, Canada, 21 to 26 January 2011. This Presentation also complements the <i>Science Signaling</i> Research Article by Stinson <i>et al.</i> published 14 June 2011.","year":2011,"lang":"en","type":"article","venue":"Science Signaling","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Genentech","keywords":"Epithelial–mesenchymal transition; Transition (genetics); Cell biology; Mesenchymal stem cell; Presentation (obstetrics); Biology; Cancer research; Chemistry; Medicine; Genetics; Surgery; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001566465,0.0003152063,0.0003040009,0.0002531858,0.0002711288,0.0004319547,0.0001664649,0.0002759134,0.00278252],"category_scores_gemma":[0.0001277896,0.0002125194,0.0002776228,0.0001398235,0.0001692354,0.0001601842,0.0002358296,0.0007587199,0.001271409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003183241,"about_ca_system_score_gemma":0.0002714609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004505298,"about_ca_topic_score_gemma":0.001299194,"domain_scores_codex":[0.9998462,0.00001846597,0.00001153505,0.0000239966,0.00005758605,0.00004214721],"domain_scores_gemma":[0.9999374,0.000007294709,0.00001776938,0.000004984408,0.00001021662,0.00002229332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002806605,0.00007830613,0.000409463,0.0001250046,0.00001069894,0.0001061459,0.00002601676,0.00006501149,0.9918234,0.0001362174,0.001001094,0.005938118],"study_design_scores_gemma":[0.0000703449,0.0007404314,0.01524298,0.00002295311,0.00005695509,0.001023181,0.0001271352,0.001566886,0.9600515,0.0001183316,0.02096614,0.00001318273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685507,0.01514979,0.004147299,0.001116965,0.0005218548,0.0001202282,0.001127749,0.0006248803,0.008640524],"genre_scores_gemma":[0.9792045,0.005778818,0.002114981,0.0002971196,0.000058751,0.00007479505,0.001143341,0.00006756306,0.01126019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00278252,"threshold_uncertainty_score":0.009308457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02556656583660626,"score_gpt":0.2929046379255186,"score_spread":0.2673380720889123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}