{"id":"W2077724030","doi":"10.1126/scisignal.2002258","title":"miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast CancerA presentation from the Keystone Symposium on Epithelial Plasticity and Epithelial to Mesenchymal Transition, Vancouver, Canada, 21 to 26 January 2011. This Presentation also complements the <i>Science Signaling</i> Research Article by Stinson <i>et al.</i> published 14 June 2011.","year":2011,"lang":"en","type":"article","venue":"Science Signaling","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":140,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Genentech","keywords":"Epithelial–mesenchymal transition; Transition (genetics); Cell biology; Mesenchymal stem cell; Presentation (obstetrics); Biology; Cancer research; Chemistry; Medicine; Genetics; Surgery; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006477221,0.0003806617,0.0005346113,0.0005098459,0.001048416,0.000239558,0.000787989,0.00006804217,0.0003183883],"category_scores_gemma":[0.0003971313,0.0002781816,0.00008681216,0.00213734,0.0008204854,0.0009595876,0.0001684781,0.0005975373,0.00002020703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005561024,"about_ca_system_score_gemma":0.001854496,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.4043882,"about_ca_topic_score_gemma":0.06704509,"domain_scores_codex":[0.9926803,0.0006103169,0.0009749582,0.001283032,0.003264244,0.001187206],"domain_scores_gemma":[0.9966291,0.0007578646,0.0002763068,0.0004692715,0.001188954,0.000678489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001641161,0.0003127844,0.0009283759,0.00003939938,0.00003227082,0.00001469645,0.02239905,0.002587256,0.9509121,0.00001930634,0.02027921,0.0008343857],"study_design_scores_gemma":[0.002482182,0.0007855115,0.01111783,0.0003528548,0.0001217547,0.00001363739,0.004856999,0.003596964,0.9750255,0.0001279169,0.001109435,0.0004094348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9693412,0.0001001868,0.002070999,0.02311951,0.000970317,0.002693451,0.001487669,0.00003702599,0.0001796479],"genre_scores_gemma":[0.9938011,0.00003486953,0.001806977,0.003713821,0.0002592595,0.0001928563,0.00005228064,0.00003894648,0.00009991939],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3373431,"threshold_uncertainty_score":0.999967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02556656583660626,"score_gpt":0.2929046379255186,"score_spread":0.2673380720889123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}