{"id":"W2077749987","doi":"10.1038/ncomms6987","title":"BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Biotechnology and Biological Sciences Research Council; Hutchison Whampoa Limited; Medical Research Council; Russian Science Foundation; King's College London; National Institute for Health and Care Research; University of Cambridge; Cancer Research UK; Wellcome Trust","keywords":"Triple-negative breast cancer; Cancer research; Gene knockdown; Breast cancer; Progenitor cell; Stem cell; Biology; Cancer stem cell; Cancer; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000836832,0.0002610477,0.0001554315,0.0003822086,0.0003328178,0.0004793628,0.0001367257,0.0002997346,0.001252081],"category_scores_gemma":[0.0001493397,0.0001264614,0.0001244993,0.0003662931,0.0003014808,0.0002128476,0.0003162342,0.0004416428,0.000488056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003905884,"about_ca_system_score_gemma":0.0002339386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007588963,"about_ca_topic_score_gemma":0.0007953782,"domain_scores_codex":[0.9998952,0.00001263761,0.000008994928,0.00002595818,0.00003923697,0.00001807163],"domain_scores_gemma":[0.9998921,0.00002042196,0.00003432628,0.000007223463,0.0000157257,0.0000301439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001354635,0.00001558919,0.002093434,0.00006638013,0.00000565872,0.0003412174,0.00003207651,0.00008989955,0.9880506,0.000432413,0.0002126951,0.008524537],"study_design_scores_gemma":[0.00003441121,0.0003560114,0.04107069,0.00004401437,0.00005066815,0.008569202,0.0002371231,0.001556133,0.9055209,0.0004959344,0.04204301,0.00002196176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781622,0.009177606,0.007156537,0.0004139735,0.00007450348,0.00004109277,0.00109373,0.000177901,0.003702452],"genre_scores_gemma":[0.9906569,0.002629732,0.001713794,0.00006118714,0.00001047667,0.00002580696,0.001057955,0.0000135759,0.003830718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001252081,"threshold_uncertainty_score":0.004188657,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04326202218700476,"score_gpt":0.3433777987545753,"score_spread":0.3001157765675705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}