{"id":"W2077823604","doi":"10.1021/bi991887i","title":"The Polar Region Consecutive to the HIV Fusion Peptide Participates in Membrane Fusion","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"","keywords":"Peptide; Amino acid; Lipid bilayer fusion; Chemistry; Peptide sequence; Membrane; Polyproline helix; Liposome; Biochemistry; Gp41; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001660941,0.0004371427,0.0002653654,0.0001093667,0.0002042516,0.0002517039,0.0001834007,0.0004989723,0.002870612],"category_scores_gemma":[0.0002831549,0.0001759545,0.0003161712,0.0001509043,0.0003640901,0.0002502436,0.0002999081,0.0004363554,0.001424219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002077642,"about_ca_system_score_gemma":0.0003247481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002551022,"about_ca_topic_score_gemma":0.0002066556,"domain_scores_codex":[0.9998826,0.00003116525,0.00001096665,0.00002530221,0.00002225268,0.00002769155],"domain_scores_gemma":[0.9997757,0.0000687868,0.00004284181,0.00002364402,0.00002123584,0.0000678622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002677879,0.00001666279,0.0002678779,0.00005604288,0.000004086294,0.000237643,0.00001298794,0.00009068878,0.9974456,0.0002071461,0.00001962484,0.001373936],"study_design_scores_gemma":[0.00006045599,0.0005812831,0.006267153,0.00002220847,0.00003859395,0.001672445,0.00003447836,0.0005920787,0.9844828,0.0001809142,0.006055336,0.00001214307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923901,0.001261172,0.003510758,0.00007847763,0.00005239706,0.00007059838,0.0001955497,0.0000349689,0.002405992],"genre_scores_gemma":[0.9929808,0.0007943697,0.003729856,0.0001078639,0.00002840973,0.00003892531,0.0003653381,0.00001758917,0.001936795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002870612,"threshold_uncertainty_score":0.009603202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376745268505065,"score_gpt":0.2552040155996845,"score_spread":0.2414365629146339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}