{"id":"W2077823604","doi":"10.1021/bi991887i","title":"The Polar Region Consecutive to the HIV Fusion Peptide Participates in Membrane Fusion","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"","keywords":"Peptide; Amino acid; Lipid bilayer fusion; Chemistry; Peptide sequence; Membrane; Polyproline helix; Liposome; Biochemistry; Gp41; Biophysics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001876729,0.0001158061,0.0001025487,0.00001577322,0.0003505776,0.00001875866,0.0002198306,0.0001154395,0.0006328374],"category_scores_gemma":[0.00009327791,0.00006191182,0.00004805523,0.000117843,0.0001833453,0.00001525521,0.0000663918,0.000200913,0.002720796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005253353,"about_ca_system_score_gemma":0.00006131964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001947214,"about_ca_topic_score_gemma":0.00008395094,"domain_scores_codex":[0.9990758,0.0001315572,0.0001499572,0.0002170373,0.0000444441,0.0003812188],"domain_scores_gemma":[0.9993916,0.0001789073,0.00002525442,0.0003384911,0.00002693693,0.0000388716],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008244714,0.0001742781,0.004742916,0.00001106048,0.00006895891,0.00005245232,0.0008563554,0.000005253737,0.9258388,0.0000236024,0.05441547,0.0129864],"study_design_scores_gemma":[0.0008633746,0.00008511483,0.005645006,0.00004858328,0.00001227728,0.00005708198,0.0006418091,0.00000377611,0.8077055,0.00002339393,0.1848052,0.0001089557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873118,0.002613931,0.000001446145,0.00556565,0.00004116693,0.0002364002,0.00005341746,0.00002245195,0.004153678],"genre_scores_gemma":[0.9777897,0.0005450901,0.000004868,0.0001520626,0.00002770697,0.00007186691,0.0001460953,0.000006744459,0.02125584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1303897,"threshold_uncertainty_score":0.9980557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01376745268505065,"score_gpt":0.2552040155996845,"score_spread":0.2414365629146339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}