{"id":"W2077952077","doi":"10.1016/j.biologicals.2011.09.005","title":"Biosimilars – Global issues, national solutions","year":2011,"lang":"en","type":"review","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Biosimilar; Biochemical engineering; Biotechnology; Biology; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009648072,0.0005849365,0.001875475,0.00009833097,0.0002398097,0.00002355331,0.0007278225,0.002437417,0.006149478],"category_scores_gemma":[0.0006297686,0.0003440834,0.0009628044,0.0004396718,0.0007060855,0.00003270556,0.0003913339,0.00057046,0.002977666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001573929,"about_ca_system_score_gemma":0.0002260251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001234078,"about_ca_topic_score_gemma":0.00000340661,"domain_scores_codex":[0.9965665,0.001060276,0.0008134618,0.000776398,0.00005306501,0.0007302653],"domain_scores_gemma":[0.9987481,0.000330041,0.0003388475,0.0003756424,0.0001401141,0.00006722994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001050281,0.0002151015,0.000006221886,0.0004608573,0.0006357212,0.000004933834,0.000002042548,7.172894e-9,0.00001152493,0.03190018,0.1351319,0.8316211],"study_design_scores_gemma":[0.0001237283,0.0001474276,0.00002684955,0.0007202913,0.0004901838,0.0001188987,0.000002410273,7.116464e-8,0.000006055631,0.003563675,0.9943399,0.0004604634],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[1.545353e-7,0.9804271,0.00007026135,0.0002383693,0.0009878441,0.0004756403,0.001642323,0.0001675022,0.01599081],"genre_scores_gemma":[0.000003021698,0.9942403,0.001385294,0.0006488496,0.0001663815,0.000088862,0.0004665422,0.00001710819,0.002983659],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.859208,"threshold_uncertainty_score":0.9999011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3109236759958771,"score_gpt":0.4379026937356841,"score_spread":0.1269790177398071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}