{"id":"W2077969282","doi":"10.1016/j.toxlet.2010.03.582","title":"Role of Phase I enzymes in benzo(a)pyrene (BP)-DNA adduct formation in normal human mammary epithelial cells (NHMECS)","year":2010,"lang":"en","type":"article","venue":"Toxicology Letters","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Adduct; Enzyme; Benzo(a)pyrene; DNA; Pyrene; Chemistry; DNA adduct; Molecular biology; Biochemistry; Biology; Carcinogen; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002181091,0.0002254411,0.0001474606,0.000308239,0.0001615839,0.0003713798,0.0001147942,0.0002361815,0.001540341],"category_scores_gemma":[0.0003007256,0.0002062621,0.0002093315,0.0001702816,0.0001958763,0.0003199559,0.0001317724,0.0002174285,0.0004746909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002314122,"about_ca_system_score_gemma":0.0002603204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001263638,"about_ca_topic_score_gemma":0.001049152,"domain_scores_codex":[0.999876,0.00003386705,0.00001401046,0.00002960513,0.00002306622,0.0000232833],"domain_scores_gemma":[0.9997565,0.0000937028,0.00003485586,0.00003752341,0.00005446872,0.00002301758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007136388,0.0000453839,0.001432929,0.00004164899,0.000007961436,0.0000614241,0.00003891053,0.00006204978,0.9956767,0.0001925575,0.00004520115,0.001681618],"study_design_scores_gemma":[0.00001811519,0.0003065642,0.009042605,0.00000376809,0.00002073778,0.0001697681,0.00004266762,0.000387391,0.9886502,0.000107637,0.001246978,0.000003550212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913827,0.002768552,0.003476565,0.0001313165,0.00003481965,0.00003495427,0.0008109656,0.00006840529,0.001291731],"genre_scores_gemma":[0.9930292,0.001073716,0.001353913,0.0000330594,0.00001249167,0.0000317694,0.0009240005,0.00001892392,0.003522835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540341,"threshold_uncertainty_score":0.005152941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006155279653212043,"score_gpt":0.2538837538425546,"score_spread":0.2477284741893425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}