{"id":"W2077993289","doi":"10.1016/j.febslet.2007.03.072","title":"Regulation of the BRCA1 promoter in ovarian surface epithelial cells and ovarian carcinoma cells","year":2007,"lang":"en","type":"article","venue":"FEBS Letters","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; University of British Columbia","funders":"","keywords":"CREB; AP-1 transcription factor; Transcription factor; Ovarian carcinoma; Cancer research; Response element; Promoter; Transcription (linguistics); Cell culture; Biology; Cell biology; Chemistry; Ovarian cancer; Gene; Gene expression; Genetics; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358201,0.0001532326,0.0002628581,0.00016299,0.0001235004,0.0002551078,0.0001168957,0.0001751238,0.001251625],"category_scores_gemma":[0.0002147929,0.000116478,0.0002041586,0.0001228458,0.0002291027,0.00009298512,0.0002163585,0.0003142509,0.0005911618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002252784,"about_ca_system_score_gemma":0.0001646968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007737668,"about_ca_topic_score_gemma":0.0008572858,"domain_scores_codex":[0.9998478,0.0000264494,0.00001141613,0.00003301902,0.00005076209,0.00003049174],"domain_scores_gemma":[0.9998505,0.0000349929,0.00003094974,0.00003366756,0.0000214429,0.0000283887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003484726,0.000004888245,0.0001690996,0.00001218533,8.738695e-7,0.00003086227,0.00002604543,0.00002952702,0.9991628,0.00005103101,0.00001365555,0.0004641451],"study_design_scores_gemma":[0.000006676352,0.00008054673,0.005478518,0.000003560914,0.000002849816,0.0003080489,0.00004951123,0.0006486815,0.991518,0.00003435264,0.001866009,0.000003395137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942128,0.0005728214,0.003490209,0.00007571307,0.00001270564,0.00001491795,0.0004541888,0.00008482009,0.00108178],"genre_scores_gemma":[0.9909327,0.0003251604,0.003987867,0.00004449197,0.000005209986,0.00003240711,0.00108218,0.00003361788,0.003556316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001251625,"threshold_uncertainty_score":0.004187167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004568275733838775,"score_gpt":0.2216891922792397,"score_spread":0.2171209165454009,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}