{"id":"W2078000524","doi":"10.1021/bi047704w","title":"UDP-<i>N</i>-acetylmuramic Acid (UDP-MurNAc) Is a Potent Inhibitor of MurA (Enolpyruvyl-UDP-GlcNAc Synthase)","year":2005,"lang":"af","type":"article","venue":"Biochemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"University of Rochester","keywords":"Biochemistry; Mura; Chemistry; Biosynthesis; Enzyme; Substrate (aquarium); ATP synthase; Escherichia coli; Peptidoglycan; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337022,0.0005616704,0.0003235944,0.0001018387,0.00009827327,0.0002722628,0.0002775434,0.0002587844,0.0009169897],"category_scores_gemma":[0.0001550344,0.0001369231,0.0002202165,0.0001241272,0.0002043712,0.000158896,0.0002235568,0.0004347443,0.0005325787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002262716,"about_ca_system_score_gemma":0.0001049577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005314228,"about_ca_topic_score_gemma":0.0003995775,"domain_scores_codex":[0.999797,0.00005915776,0.00001908451,0.000043559,0.00004805586,0.00003315912],"domain_scores_gemma":[0.9998976,0.00001929971,0.00002933602,0.00001117617,0.00001326833,0.00002934897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004470369,0.00001241272,0.0001103893,0.00003336794,0.000005060273,0.00001600842,0.000003436678,0.0000405719,0.9982675,0.00003122678,0.00001715339,0.001418013],"study_design_scores_gemma":[0.000004051647,0.0001803167,0.001141502,0.000002925063,0.000006219773,0.000204607,0.000003694662,0.0003504822,0.995876,0.00001376655,0.002214146,0.000002336173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9640857,0.009868663,0.02008219,0.0001045057,0.00006866014,0.00008538392,0.0004091481,0.00037863,0.004917221],"genre_scores_gemma":[0.9842061,0.001737283,0.009378386,0.0000818398,0.00002040043,0.00004027141,0.0009667572,0.00003596574,0.003532977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009169897,"threshold_uncertainty_score":0.003067613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009736168838176592,"score_gpt":0.261134917583354,"score_spread":0.2513987487451774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}