{"id":"W2078069118","doi":"10.1021/bi012031s","title":"Mechanistic Studies of a Retaining α-Galactosyltransferase from <i>Neisseria meningitidis</i>","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences; University of British Columbia","funders":"University of British Columbia; University of Alberta","keywords":"Galactosyltransferase; Glycoconjugate; Chemistry; Anomer; Moiety; Glycosyl; Neisseria meningitidis; Substrate (aquarium); Enzyme; Stereochemistry; Yield (engineering); Levansucrase; Glycosylation; Enzyme catalysis; Oligosaccharide; Catalysis; Biochemistry; Bacteria; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003704976,0.0003252811,0.0001856161,0.00006271014,0.0001921071,0.0003773149,0.0003852805,0.0003426929,0.000323254],"category_scores_gemma":[0.0002507575,0.000110666,0.0001919766,0.00007571535,0.000335665,0.00047345,0.0001532524,0.0005697865,0.0001495154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006476652,"about_ca_system_score_gemma":0.0003877146,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00174549,"about_ca_topic_score_gemma":0.001623044,"domain_scores_codex":[0.9999073,0.00001825182,0.00000654195,0.00001549012,0.00003171974,0.00002069495],"domain_scores_gemma":[0.9999326,0.00001617063,0.00001972818,0.000007614629,0.000009130395,0.00001453866],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001786251,0.0001033954,0.0007824295,0.000149614,0.00001405823,0.0002862233,0.00008135092,0.001381784,0.9908318,0.002396279,0.00004645369,0.003748032],"study_design_scores_gemma":[0.00001338259,0.0002142651,0.0009695031,0.00000495046,0.00001794881,0.0003188099,0.00005504415,0.003262535,0.9926894,0.0003141816,0.002133732,0.000006120469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905626,0.00138359,0.006082386,0.0001792834,0.00001364174,0.00004345328,0.00007388368,0.00003165095,0.001629433],"genre_scores_gemma":[0.9938167,0.0008438148,0.004158247,0.00003477417,0.000003125013,0.00001455704,0.00009857629,0.000004924421,0.001025425],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00174549,"threshold_uncertainty_score":0.004699171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03277170786125599,"score_gpt":0.2561221959706613,"score_spread":0.2233504881094053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}