{"id":"W2078074828","doi":"10.4161/rna.4.2.5039","title":"Secondary Structure and Dynamics of the r(CGG) Repeat in the mRNA of the Fragile X Mental Retardation 1<i>(FMR1)</i>Gene","year":2007,"lang":"en","type":"article","venue":"RNA Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Fragile X syndrome; FMR1; Biology; Ataxia; Genetics; Gene; RNA; Fragile x; Protein secondary structure; Trinucleotide repeat expansion; Untranslated region; Base pair; Messenger RNA; Stem-loop; Molecular biology; Allele; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001873504,0.00008914455,0.00009213704,0.00001814438,0.00006472414,0.000002897915,0.0002693214,0.0001155749,0.000009810155],"category_scores_gemma":[0.0000333234,0.00004767719,0.00004719936,0.00009373295,0.0002099748,0.000001317032,0.0001701679,0.0001055111,1.153222e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008011581,"about_ca_system_score_gemma":0.0000312046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004027627,"about_ca_topic_score_gemma":0.0008843086,"domain_scores_codex":[0.9993455,0.00008730379,0.0002055586,0.0001710065,0.00006355706,0.0001270231],"domain_scores_gemma":[0.9995522,0.0000153172,0.0001189272,0.0002778721,0.00002292654,0.00001272082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002959379,0.00001712097,0.04380612,0.000008155424,0.00001451598,1.81226e-7,0.0001576097,0.0000074746,0.9527894,0.0001616903,0.0001003368,0.002907785],"study_design_scores_gemma":[0.0002976487,0.00008877647,0.4691081,0.000005216758,0.000007788566,0.00001562228,0.0001864251,0.00002454038,0.5277151,0.0005219441,0.001965765,0.00006301936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979569,0.000498514,0.00002801946,0.0004376991,0.0001947357,0.0001861913,0.00009892148,9.661499e-7,0.0005980692],"genre_scores_gemma":[0.9991572,0.0001946919,0.0001065908,0.00038684,0.00001231904,0.000001693089,0.00009788344,0.000006376858,0.00003641015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.425302,"threshold_uncertainty_score":0.1944219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003723902263616423,"score_gpt":0.2105176779286323,"score_spread":0.2067937756650158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}