{"id":"W2078074828","doi":"10.4161/rna.4.2.5039","title":"Secondary Structure and Dynamics of the r(CGG) Repeat in the mRNA of the Fragile X Mental Retardation 1<i>(FMR1)</i>Gene","year":2007,"lang":"en","type":"article","venue":"RNA Biology","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","keywords":"Fragile X syndrome; FMR1; Biology; Ataxia; Genetics; Gene; RNA; Fragile x; Protein secondary structure; Trinucleotide repeat expansion; Untranslated region; Base pair; Messenger RNA; Stem-loop; Molecular biology; Allele; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009827234,0.0001012243,0.00009947984,0.0001220639,0.000159092,0.000191204,0.000115008,0.0001618958,0.0005941095],"category_scores_gemma":[0.0002660463,0.00008701448,0.0001050492,0.00008472471,0.0001905862,0.0001421068,0.00006783704,0.000249733,0.0001746765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002755265,"about_ca_system_score_gemma":0.0000991221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008160776,"about_ca_topic_score_gemma":0.0009070358,"domain_scores_codex":[0.9999648,0.000006984683,0.000001377926,0.000009346754,0.000009362901,0.000008036079],"domain_scores_gemma":[0.99985,0.0000405219,0.00005737888,0.000005992997,0.0000186377,0.00002753452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001875268,0.00003862265,0.00258291,0.00003267095,0.00001582091,0.0002113185,0.0001583489,0.001146812,0.992999,0.0003242185,0.000134812,0.00216804],"study_design_scores_gemma":[0.00005490056,0.001020229,0.1274063,0.00003273869,0.0000788562,0.0007557006,0.0002285881,0.03013594,0.8360438,0.000942193,0.003244085,0.00005662578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989659,0.0001945006,0.0004168033,0.00003319253,0.000004522998,0.000002496334,0.00003793006,0.00001410754,0.0003305327],"genre_scores_gemma":[0.9992658,0.00009206887,0.0003000244,0.00001829867,0.00000527489,0.000004617178,0.00007459776,0.000006984489,0.0002322963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008160776,"threshold_uncertainty_score":0.00199908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003723902263616423,"score_gpt":0.2105176779286323,"score_spread":0.2067937756650158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}