{"id":"W2078095360","doi":"10.1371/journal.pone.0001227","title":"Transforming Growth Factor: β Signaling Is Essential for Limb Regeneration in Axolotls","year":2007,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":149,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"Canadian Institutes of Health Research; Zentrum für Regenerative Therapien Dresden; Réseau de Recherche en Santé Buccodentaire et Osseuse","keywords":"Axolotl; Regeneration (biology); Wound healing; Biology; Regenerative process; Cell biology; Transforming growth factor; Transforming growth factor beta; Limb development; Anatomy; Immunology; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005639131,0.0002997443,0.0001713216,0.0002894646,0.0002348905,0.0002712705,0.0001744901,0.0002572109,0.001179328],"category_scores_gemma":[0.0000913073,0.00018449,0.000256705,0.0001407008,0.0002302952,0.000165454,0.0001880434,0.0006606134,0.0005752665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003015846,"about_ca_system_score_gemma":0.0002747125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001410753,"about_ca_topic_score_gemma":0.002162683,"domain_scores_codex":[0.9999154,0.000006404985,0.000006593948,0.00002198861,0.00002234958,0.0000273955],"domain_scores_gemma":[0.9998703,0.00002192656,0.00004759619,0.000007523653,0.00001328752,0.00003939452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003506281,0.000005155249,0.0001869272,0.0000132972,9.337153e-7,0.00004574588,0.00001145668,0.00001140087,0.9993575,0.00002173417,0.00001851033,0.0002922686],"study_design_scores_gemma":[0.00005670609,0.0003356156,0.1066533,0.00003096487,0.00003727576,0.0008210402,0.0001836069,0.001131361,0.8825719,0.0001056596,0.008053768,0.00001891147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994302,0.001838237,0.001367492,0.0001310705,0.00002633806,0.00001482763,0.0008771784,0.0001104571,0.001332428],"genre_scores_gemma":[0.9886922,0.001337024,0.001584181,0.0001571909,0.00002210737,0.00005212843,0.002997617,0.0000518767,0.005105701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001410753,"threshold_uncertainty_score":0.003945291,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02340934106548886,"score_gpt":0.2448519101716861,"score_spread":0.2214425691061972,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}