{"id":"W2078109375","doi":"10.1039/b926078a","title":"Streptococcus pneumoniae endohexosaminidase D; feasibility of using N-glycan oxazoline donors for synthetic glycosylation of a GlcNAc-asparagine acceptor","year":2010,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Victoria","funders":"","keywords":"Oxazoline; Chemistry; Glycoconjugate; Glycosylation; Glycan; Biocatalysis; Asparagine; Glycosyl; Hydrolysis; Stereochemistry; Biochemistry; Glycosyltransferase; Glycoside hydrolase; Enzyme; Combinatorial chemistry; Glycoprotein; Reaction mechanism; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001819222,0.0003067735,0.000116046,0.0001047681,0.00005809,0.0002560545,0.0001516817,0.0001659718,0.0002867141],"category_scores_gemma":[0.0001093463,0.00008086864,0.00007646153,0.0001501282,0.0001683382,0.0001295991,0.0002465262,0.0001972798,0.0002086794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003036309,"about_ca_system_score_gemma":0.0002595034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007049734,"about_ca_topic_score_gemma":0.0008206642,"domain_scores_codex":[0.9998775,0.00003347477,0.0000100147,0.00002757701,0.00003360219,0.00001780896],"domain_scores_gemma":[0.9999548,0.000008085466,0.00001518819,0.000005233329,0.000004937694,0.00001186565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001178651,0.00001754395,0.0002291616,0.00006322888,0.000002775236,0.00004934767,0.00001188688,0.0001980796,0.9942331,0.0002827656,0.00002858828,0.004765825],"study_design_scores_gemma":[0.000009554622,0.0001124563,0.0004053771,0.000003500314,0.000005112402,0.0001017505,0.000006977144,0.0005169507,0.9951562,0.00002837734,0.003651196,0.000002617552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973694,0.002807169,0.01810053,0.00006668038,0.00002068437,0.00005153279,0.0002545778,0.0000875907,0.004917369],"genre_scores_gemma":[0.9785364,0.001687308,0.01682864,0.00002052442,0.000002437422,0.0000135325,0.000271344,0.000016769,0.002623101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007049734,"threshold_uncertainty_score":0.002202988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01892090537947682,"score_gpt":0.3072310170795249,"score_spread":0.2883101117000481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}