{"id":"W2078168921","doi":"10.1016/j.bpj.2013.11.3378","title":"Molecular Dynamics-Based Predictions of the Structural and Functional Differences Between the Cardiac and Novel Slow-Skeletal Isoforms of Zebrafish Troponin C","year":2014,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; Simon Fraser University","funders":"","keywords":"Gene isoform; Zebrafish; Troponin C; Troponin complex; Troponin T; Linker; Biology; Troponin; Cell biology; Messenger RNA; Troponin I; Biophysics; Chemistry; Molecular biology; Biochemistry; Gene; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001993648,0.0005333493,0.0003174773,0.0003383705,0.000653538,0.0004203027,0.0006496354,0.0005694421,0.001819386],"category_scores_gemma":[0.000600113,0.0002997438,0.000385782,0.0001990552,0.0004052586,0.0004435069,0.0002363935,0.0006524921,0.0002788667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009697122,"about_ca_system_score_gemma":0.001185937,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01331791,"about_ca_topic_score_gemma":0.0132827,"domain_scores_codex":[0.9999657,0.000005548938,0.000001520985,0.000008190778,0.000009056617,0.00001000269],"domain_scores_gemma":[0.9998546,0.00004504892,0.00001881916,0.000009591322,0.00004083586,0.00003100918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000185829,0.0001029052,0.002192517,0.00006449319,0.0000339317,0.0001713599,0.00007220394,0.9513006,0.02994023,0.01046552,0.000820852,0.004649501],"study_design_scores_gemma":[0.00002514521,0.00001558795,0.0005233939,0.0000022961,0.000004636294,0.000007684428,0.00001323241,0.9975522,0.0008352067,0.0009002777,0.0001152587,0.000005018062],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.956136,0.0002389292,0.0341745,0.0005139124,0.00006272682,0.0000519784,0.0004148323,0.0003024078,0.008104705],"genre_scores_gemma":[0.9922138,0.0001211237,0.006717285,0.00004207086,0.000009884183,0.00004172965,0.000251471,0.00006487378,0.0005376627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01331791,"threshold_uncertainty_score":0.02648079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008076330131092501,"score_gpt":0.1925363388256889,"score_spread":0.1844600086945964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}