{"id":"W2078204057","doi":"10.1081/lpr-120026389","title":"Targeting of Lipid-Protamine-DNA (LPD) Lipopolyplexes Using RGD Motifs","year":2003,"lang":"en","type":"article","venue":"Journal of Liposome Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Celator Pharmaceuticals (Canada)","funders":"","keywords":"Transfection; Protamine; PEGylation; Chemistry; Gene delivery; Integrin; Liposome; Peptide; PEG ratio; Molecular biology; Biophysics; Biochemistry; Cell biology; Receptor; Biology; Polyethylene glycol; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002321329,0.0003038951,0.0002937879,0.0002062952,0.00009490739,0.0003578646,0.0001901049,0.0004841434,0.0005429778],"category_scores_gemma":[0.0002437845,0.0001764979,0.0002086854,0.0001833645,0.0002456064,0.0002536797,0.0002346747,0.00041445,0.0003953869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005338536,"about_ca_system_score_gemma":0.0001739305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003217591,"about_ca_topic_score_gemma":0.0003516462,"domain_scores_codex":[0.999806,0.00003110076,0.00002691588,0.00006856515,0.00003922509,0.00002824453],"domain_scores_gemma":[0.9998761,0.00003780507,0.00004460078,0.00001022513,0.00001237859,0.00001882657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005009216,0.00001809376,0.00005704774,0.00002485369,0.000003966637,0.00003733765,0.000009525001,0.0001051088,0.9983379,0.0000742431,0.00002781786,0.001254015],"study_design_scores_gemma":[0.00001565436,0.0001754688,0.0002553986,0.000001897755,0.000008499754,0.00009782956,0.000003251818,0.0009859023,0.9972181,0.0000178305,0.00121717,0.00000278104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804125,0.001092707,0.01671397,0.0001241993,0.00003774322,0.0001436361,0.0002286178,0.0001831297,0.001063576],"genre_scores_gemma":[0.9789497,0.0006679756,0.01764724,0.00008839602,0.0000111908,0.0001289913,0.0004160198,0.00004036711,0.002050026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005429778,"threshold_uncertainty_score":0.003873348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07170969116373574,"score_gpt":0.373502541785421,"score_spread":0.3017928506216853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}