{"id":"W2078228116","doi":"10.1021/ed200426m","title":"The Petasis Reaction: Microscale Synthesis of a Tertiary Amine Antifungal Analog","year":2012,"lang":"en","type":"article","venue":"Journal of Chemical Education","topic":"Chemistry and Chemical Engineering","field":"Environmental Science","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Stereocenter; Antifungal; Microscale chemistry; Chemistry; Tertiary amine; Amine gas treating; Combinatorial chemistry; Organic chemistry; Biochemical engineering; Mathematics education; Enantioselective synthesis; Engineering","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002147091,0.00006731324,0.000106162,0.00001065406,0.00002885263,0.00000811768,0.0001552317,0.0000502086,0.0001672885],"category_scores_gemma":[0.0003608615,0.00004722012,0.00008964495,0.0001098387,0.00009300932,0.0001764701,0.00003182466,0.0001511059,0.00000785027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001122595,"about_ca_system_score_gemma":0.0000199181,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006000403,"about_ca_topic_score_gemma":8.767346e-8,"domain_scores_codex":[0.9993227,0.00001010401,0.000291882,0.00005570398,0.0001856654,0.0001340098],"domain_scores_gemma":[0.9993658,0.0001829619,0.0002047331,0.000113676,0.00002124283,0.00011155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001579339,0.0001758173,0.006608271,0.00001342435,0.0000114373,1.234406e-7,0.00004791033,0.000003451647,0.9781953,0.000003360561,0.003264672,0.01166044],"study_design_scores_gemma":[0.00004843283,0.000004520208,0.01069026,0.00003022033,0.00003486338,0.00008569509,0.00007432204,0.00001432109,0.9821917,0.00003986342,0.006732163,0.00005364877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970331,0.0002722415,0.00002701181,0.0004411439,0.0002045564,0.00001995226,9.638206e-7,0.000003444296,0.00199758],"genre_scores_gemma":[0.9989232,0.00004459035,0.0005846156,0.00003080012,0.000314572,0.000002529596,0.000001199094,0.000005423593,0.00009304229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01160679,"threshold_uncertainty_score":0.1925581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003748779440591962,"score_gpt":0.2170342412888029,"score_spread":0.213285461848211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}