{"id":"W2078313196","doi":"10.1128/mcb.23.18.6494-6506.2003","title":"Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":468,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; Ministero dell’Istruzione, dell’Università e della Ricerca; Arthritis Society","keywords":"Endosome; Phagosome; Cell biology; Endocytic cycle; Biology; Dynein; Dynactin; Microtubule; Rab; Lipid bilayer fusion; Endocytosis; GTPase; Intracellular; Biochemistry; Membrane; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001647744,0.000242634,0.0003785086,0.0000766179,0.00007136649,0.000008636977,0.00007629884,0.0002380481,0.00001801797],"category_scores_gemma":[0.0000267758,0.0001828753,0.0000669199,0.0000900155,0.0003956536,0.000006317005,0.00005113603,0.00008385913,2.789023e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002475635,"about_ca_system_score_gemma":0.00004308432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005247409,"about_ca_topic_score_gemma":0.00002387638,"domain_scores_codex":[0.998772,0.0001274606,0.0003013545,0.0004728061,0.00008270302,0.000243724],"domain_scores_gemma":[0.9994011,0.00001713095,0.0001342115,0.00027059,0.00007123363,0.0001057303],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002744394,0.00008306546,0.01146791,0.00009909468,0.0001103105,0.00001391564,0.0001371479,0.000002265511,0.986452,0.00048477,0.000002539053,0.0008724919],"study_design_scores_gemma":[0.001404452,0.0007932293,0.0004921287,0.00003436264,0.00009523562,0.00006853957,0.0001637181,0.00001933845,0.989732,0.0002175588,0.006751589,0.0002278168],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973004,0.02324823,0.00316011,0.0000391571,0.00002240065,0.0003673144,0.00004222697,0.000007809932,0.0001087601],"genre_scores_gemma":[0.9953683,0.003017738,0.00073979,0.00006029465,0.00001059578,0.000019377,0.0006390219,0.00002686795,0.0001180427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02236428,"threshold_uncertainty_score":0.7457439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004099314818544965,"score_gpt":0.195413118067457,"score_spread":0.1913138032489121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}