{"id":"W2078339523","doi":"10.1006/bbrc.2001.4703","title":"xCT Cystine Transporter Expression in HEK293 Cells: Pharmacology and Localization","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"HEK 293 cells; Transporter; Transfection; Cystine; Xenopus; Protein subunit; Cell biology; Intracellular; Chemistry; Solute carrier family; Biochemistry; Biology; Molecular biology; Cysteine; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002536622,0.0001103002,0.0001372355,0.00006203325,0.0001409386,0.00001937038,0.0002861148,0.0001415974,0.00001444359],"category_scores_gemma":[0.00004145707,0.00009056115,0.0000322606,0.0002239303,0.0005673505,0.000007544459,0.0003015287,0.0002502042,0.000004401376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009047435,"about_ca_system_score_gemma":0.00002903011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003882745,"about_ca_topic_score_gemma":0.00001071485,"domain_scores_codex":[0.9989483,0.0001637066,0.0001734408,0.0002972036,0.0001433324,0.0002739564],"domain_scores_gemma":[0.9992564,0.00006748929,0.00002381394,0.0004077175,0.00009221272,0.0001523722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009343976,0.0002115466,0.0005322492,0.00001448121,0.000006172149,0.000001646147,0.00005732971,9.896311e-7,0.9949188,0.0001306523,0.001956515,0.002076143],"study_design_scores_gemma":[0.0006694489,0.0001235682,0.003830643,0.00002697079,0.00001039331,0.000007194889,0.0001188899,0.001100298,0.9125706,0.0001550067,0.08123308,0.0001539158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936849,0.003866569,0.0006800285,0.001106683,0.00002306155,0.0002005734,0.00001470832,0.000009711309,0.000413712],"genre_scores_gemma":[0.988268,0.01025761,0.0007642141,0.0001595769,0.0001366934,0.00005468518,0.0001371964,0.00001111893,0.0002109694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08234824,"threshold_uncertainty_score":0.3692977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03884697283379828,"score_gpt":0.3577664570507159,"score_spread":0.3189194842169176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}