{"id":"W2078369153","doi":"10.1371/journal.pone.0049959","title":"A Conserved C-Terminal Domain of the Aspergillus fumigatus Developmental Regulator MedA Is Required for Nuclear Localization, Adhesion and Virulence","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie – Hans-Knöll-Institut; Leibniz-Gemeinschaft; Canadian Institutes of Health Research","keywords":"Nuclear localization sequence; Biology; Virulence; Nuclear transport; Cell biology; Aspergillus fumigatus; Regulator; Genetics; Microbiology; Cell nucleus; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009990592,0.0003341938,0.0002582442,0.0001920018,0.0002220147,0.0002455199,0.0001816564,0.0002098505,0.001146042],"category_scores_gemma":[0.000202763,0.000168146,0.0003249296,0.0001123241,0.0003485798,0.0001731851,0.0003262802,0.0004488315,0.0008659823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003466893,"about_ca_system_score_gemma":0.0003184218,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006600891,"about_ca_topic_score_gemma":0.0008253971,"domain_scores_codex":[0.9998877,0.00001842713,0.00001335159,0.00002922679,0.00003289038,0.00001838586],"domain_scores_gemma":[0.9997904,0.0000414667,0.00005659896,0.00002678941,0.00002021922,0.000064484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005805902,0.000009180534,0.00032275,0.0000226817,0.000002370992,0.0000810529,0.000007681061,0.00007978472,0.9985093,0.0001310388,0.00002046643,0.0007555192],"study_design_scores_gemma":[0.00002154434,0.0001430773,0.02031443,0.00001068991,0.00001883215,0.0009097573,0.00004377935,0.001714747,0.9725379,0.0001958624,0.004076919,0.00001253057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912325,0.001069139,0.005841183,0.0001139638,0.00002121433,0.00002083947,0.0006050617,0.0001164974,0.0009795229],"genre_scores_gemma":[0.9956282,0.0001513899,0.002607583,0.00002767065,0.000005612799,0.000009652273,0.0007706807,0.00001296291,0.0007863641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001146042,"threshold_uncertainty_score":0.00383389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04753855690212135,"score_gpt":0.2497940523804583,"score_spread":0.202255495478337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}