{"id":"W2078430732","doi":"10.1530/rep-09-0024","title":"The genetics of induced pluripotency","year":2009,"lang":"en","type":"review","venue":"Reproduction","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; Ontario Institute for Cancer Research","funders":"Canadian Institutes of Health Research","keywords":"Reprogramming; Induced pluripotent stem cell; Embryonic stem cell; Biology; Stem cell; Homeobox protein NANOG; Genetics; Cell biology; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007460059,0.0009324054,0.0008477612,0.001526767,0.0002424535,0.0008576997,0.0009850909,0.001074542,0.001960121],"category_scores_gemma":[0.0005277782,0.000340955,0.0003944835,0.001406078,0.001435777,0.001249863,0.0007774575,0.002314141,0.003149424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001075221,"about_ca_system_score_gemma":0.0007452768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008062741,"about_ca_topic_score_gemma":0.0007027555,"domain_scores_codex":[0.9996982,0.00005101742,0.00003057893,0.0000546977,0.000145963,0.00001947675],"domain_scores_gemma":[0.9998174,0.00007703534,0.00002368159,0.00002275428,0.00004228223,0.00001683185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006105063,0.00006649445,0.0002507962,0.005396593,0.0000589165,0.0005701553,0.0001129105,0.0007844393,0.02614002,0.06552033,0.04133494,0.8597034],"study_design_scores_gemma":[0.00001071784,0.00002823544,0.0003006604,0.0005911132,0.00001703388,0.0009099406,0.00001752677,0.0000682712,0.003923711,0.007570306,0.9865485,0.00001395953],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000490825,0.9850085,0.004164733,0.001049222,0.001007761,0.00001416035,0.00005976885,0.00007091434,0.008134155],"genre_scores_gemma":[0.002647643,0.9898884,0.001857506,0.0007884535,0.0002609615,0.00002510615,0.00008339702,0.00001250648,0.004435931],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001960121,"threshold_uncertainty_score":0.007801354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04862161147021416,"score_gpt":0.3432676945804903,"score_spread":0.2946460831102761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}