{"id":"W2078434918","doi":"10.1128/jvi.74.16.7349-7361.2000","title":"Identification of Domains of the Human Papillomavirus Type 11 E1 Helicase Involved in Oligomerization and Binding to the Viral Origin","year":2000,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"","keywords":"Biology; Helicase; Minichromosome maintenance; DNA replication; Amino acid; DNA; Origin recognition complex; Viral replication; Replication factor C; Control of chromosome duplication; SeqA protein domain; Molecular biology; Cell biology; Biochemistry; Eukaryotic DNA replication; Virus; Virology; Gene; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005807651,0.00006185005,0.000134487,0.00008778238,0.00004800262,0.000006118517,0.0002261899,0.00007561309,0.00002757657],"category_scores_gemma":[0.00005692443,0.00003986699,0.00004561948,0.0001821561,0.0001164397,0.000005007684,0.00003929316,0.00009944981,0.000001752293],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001307172,"about_ca_system_score_gemma":0.00005198525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002056301,"about_ca_topic_score_gemma":0.0002975641,"domain_scores_codex":[0.9990732,0.0002271692,0.0003691469,0.00009411155,0.0001248715,0.0001115072],"domain_scores_gemma":[0.9994521,0.00001602408,0.0002161256,0.0002047096,0.00007984544,0.00003121096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006778748,0.00004712414,0.01136334,0.000005516803,0.00002264784,0.000001494059,0.0001220684,0.0004026414,0.985923,0.00003277105,0.00004034053,0.001361191],"study_design_scores_gemma":[0.000699323,0.001616113,0.0338172,0.00001174218,0.00001463614,0.00001968161,0.00005614911,0.00004013122,0.9619842,0.0001246596,0.001565981,0.00005024278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989768,0.0003111073,0.00003007538,0.0004834284,0.00005460501,0.0001201596,0.000005879274,6.325391e-7,0.00001731234],"genre_scores_gemma":[0.9993042,0.0003543062,0.00002306763,0.0001557918,0.00007271386,0.000002298464,0.000003287541,0.000007874612,0.00007650821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02393885,"threshold_uncertainty_score":0.1625729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0191506422237427,"score_gpt":0.3204583822883273,"score_spread":0.3013077400645847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}