{"id":"W2078468171","doi":"10.1097/00024382-200116050-00007","title":"ANTIOXIDANTS INCREASE LIPOPOLYSACCHARIDE-STIMULATED TNFα RELEASE IN MURINE MACROPHAGES: ROLE FOR ALTERED TNFα mRNA STABILITY","year":2001,"lang":"en","type":"article","venue":"Shock","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital; University of Toronto; Toronto General Hospital","funders":"","keywords":"Pyrrolidine dithiocarbamate; Tumor necrosis factor alpha; Molecular biology; Proinflammatory cytokine; Cytokine; NFKB1; Chemistry; Gene expression; Biology; Cell biology; NF-κB; Inflammation; Transcription factor; Immunology; Signal transduction; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003233363,0.0005378682,0.0004604479,0.0003384074,0.00014046,0.000405984,0.0001112631,0.0003615061,0.001218021],"category_scores_gemma":[0.0002583136,0.0002208892,0.0003811416,0.0001952205,0.0003917485,0.0002863469,0.00017734,0.0005719701,0.0005276587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000270448,"about_ca_system_score_gemma":0.0001988182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002313937,"about_ca_topic_score_gemma":0.0002789371,"domain_scores_codex":[0.9998217,0.0000391681,0.00002495274,0.00003469195,0.00003985292,0.00003969527],"domain_scores_gemma":[0.9995762,0.0000749242,0.00015407,0.00005085198,0.00007700118,0.00006707021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003212932,0.00001745303,0.00007384748,0.00002657815,0.000002707994,0.00002369692,0.0000117863,0.0000114763,0.999191,0.000007839414,0.000005070444,0.0003073192],"study_design_scores_gemma":[0.00003701809,0.0006975672,0.003738443,0.00001107499,0.00002091231,0.0001427664,0.0000303851,0.0002064686,0.9943671,0.00003292058,0.0007105606,0.000004808772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909764,0.005693013,0.00218657,0.0001282931,0.00006132771,0.0000460508,0.0003222629,0.00007286228,0.0005133442],"genre_scores_gemma":[0.9905869,0.002794117,0.003502668,0.0001343408,0.00005959148,0.00008303241,0.0005659832,0.00003911811,0.002234131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001218021,"threshold_uncertainty_score":0.004074693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0143722596892427,"score_gpt":0.2512552638511819,"score_spread":0.2368830041619392,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}