{"id":"W2078477504","doi":"10.1016/j.cell.2004.05.024","title":"CDK Activity Antagonizes Whi5, an Inhibitor of G1/S Transcription in Yeast","year":2004,"lang":"en","type":"article","venue":"Cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":464,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; University of New Brunswick","funders":"","keywords":"Cyclin-dependent kinase; Biology; Cell biology; E2F; CDK inhibitor; Phosphorylation; Transcription (linguistics); Cell cycle; Transcription factor; Retinoblastoma protein; Cyclin A; Molecular biology; Biochemistry; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005704749,0.00007191519,0.00008431746,0.00002305509,0.00001490519,0.000006512961,0.00007945878,0.00008984029,0.000005198063],"category_scores_gemma":[0.000002828946,0.00007557109,0.00003832009,0.00003993469,0.00002892608,0.000003432216,0.00001732361,0.00004572618,0.000002723383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000154919,"about_ca_system_score_gemma":0.00004534434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005465305,"about_ca_topic_score_gemma":0.0002189888,"domain_scores_codex":[0.9995791,0.00001526973,0.0001028355,0.0001526894,0.00004450639,0.0001056535],"domain_scores_gemma":[0.9997407,8.387211e-7,0.00004167663,0.0001637086,0.00001961366,0.00003346344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003182521,0.0001769114,0.0003551941,0.000024097,0.000002771415,0.000001000558,0.0001049114,0.0004936045,0.9983274,0.00001980056,0.000008441345,0.0004540619],"study_design_scores_gemma":[0.0006804608,0.0001881314,0.005605999,0.000007297299,0.000004311886,0.000001892339,0.00008665919,0.0001268988,0.9927439,0.0001149751,0.0003503843,0.00008909689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984595,0.00009491303,0.0005247813,0.00002475867,0.00008275954,0.0000729451,0.0000224026,0.000003503899,0.0007144642],"genre_scores_gemma":[0.9991348,0.00007288902,0.000566444,0.00001952413,0.00005945465,0.00000299455,0.00005499841,0.00001086461,0.00007802366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005583488,"threshold_uncertainty_score":0.3081699,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006244791017468519,"score_gpt":0.2097690862450803,"score_spread":0.2035242952276118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}