{"id":"W2078477504","doi":"10.1016/j.cell.2004.05.024","title":"CDK Activity Antagonizes Whi5, an Inhibitor of G1/S Transcription in Yeast","year":2004,"lang":"en","type":"article","venue":"Cell","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":464,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; University of New Brunswick","funders":"","keywords":"Cyclin-dependent kinase; Biology; Cell biology; E2F; CDK inhibitor; Phosphorylation; Transcription (linguistics); Cell cycle; Transcription factor; Retinoblastoma protein; Cyclin A; Molecular biology; Biochemistry; Cell; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001345584,0.0003953319,0.0002783813,0.0003925227,0.0003339728,0.0005550417,0.0004485817,0.0002357628,0.002151126],"category_scores_gemma":[0.0002040332,0.0002110715,0.0002465589,0.0002139306,0.0003843139,0.000229897,0.0003872112,0.0004676134,0.0005094762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007213118,"about_ca_system_score_gemma":0.0004144163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002741712,"about_ca_topic_score_gemma":0.005071847,"domain_scores_codex":[0.9998796,0.00001311729,0.00001124113,0.00002140762,0.00002604168,0.00004872651],"domain_scores_gemma":[0.9998434,0.00003983441,0.00003175933,0.00002019071,0.00001251391,0.00005238986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004518268,0.00003811111,0.0003306148,0.00005372324,0.000008909444,0.0001321459,0.0000130952,0.0003381396,0.9958015,0.0004699822,0.0001270329,0.002234928],"study_design_scores_gemma":[0.00001966512,0.00009052546,0.00120735,0.000003343843,0.000009440511,0.0001193181,0.00002335622,0.0009432102,0.9959047,0.00005672318,0.001619101,0.000003206717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903744,0.002729397,0.001796154,0.0001850872,0.00004946592,0.00001768058,0.0003050608,0.0001641468,0.004378602],"genre_scores_gemma":[0.9972497,0.000522869,0.0006425746,0.00004555672,0.00000759498,0.000005758011,0.0002325859,0.00003415195,0.00125915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002741712,"threshold_uncertainty_score":0.007196248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006244791017468519,"score_gpt":0.2097690862450803,"score_spread":0.2035242952276118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}