{"id":"W2078508114","doi":"10.1074/jbc.m112.356253","title":"Histone H2B Ubiquitylation Promotes Activity of the Intact Set1 Histone Methyltransferase Complex in Fission Yeast","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Histone methyltransferase; Histone methylation; Histone H2A; Histone code; Histone H2B; Histone H1; Histone H3; Cell biology; Chromatin; Biology; Histone; Chromatin immunoprecipitation; Chemistry; Molecular biology; Nucleosome; Biochemistry; DNA methylation; DNA; Gene expression; Gene; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001306138,0.0004537031,0.0003340594,0.0002612444,0.0002483814,0.0004409462,0.0003256633,0.0002229072,0.0009311123],"category_scores_gemma":[0.0001472911,0.0002908172,0.0003398024,0.0002059646,0.0002099177,0.0001613364,0.0004960837,0.0004592891,0.0004471147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007354848,"about_ca_system_score_gemma":0.0002246679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002143812,"about_ca_topic_score_gemma":0.003126186,"domain_scores_codex":[0.9998482,0.00001403627,0.00001730566,0.00004202392,0.00005231517,0.00002607188],"domain_scores_gemma":[0.9998853,0.00001613326,0.00002389596,0.00001720041,0.00001190722,0.00004554376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000865544,0.000009429875,0.0002756552,0.00002249649,0.000007370249,0.00004475608,0.00002178778,0.000063723,0.9989257,0.00007254216,0.00002778369,0.0004420686],"study_design_scores_gemma":[0.00001839277,0.00008242555,0.008908095,0.000007316472,0.00001869039,0.0001973149,0.00003820484,0.001199405,0.987415,0.00005898322,0.002046536,0.000009663888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964917,0.0009205144,0.001359884,0.00006398868,0.00001314019,0.00001088629,0.0005263994,0.0000745841,0.0005388688],"genre_scores_gemma":[0.9950095,0.0004182628,0.001445133,0.00002533549,0.000004098888,0.00001304986,0.001514807,0.00003818153,0.001531508],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002143812,"threshold_uncertainty_score":0.005336404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02591164552489414,"score_gpt":0.2896221352449773,"score_spread":0.2637104897200832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}