{"id":"W2078570791","doi":"10.3390/ph4040665","title":"A Novel Behavioral Fish Model of Nociception for Testing Analgesics","year":2011,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Morphine; Nociception; Noxious stimulus; Analgesic; Pharmacology; Stimulus (psychology); Medicine; Opioid; Anesthesia; Opioid antagonist; (+)-Naloxone; Neuroscience; Psychology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000218584,0.0009452605,0.0004350245,0.0005817827,0.0002897393,0.0002083897,0.0006456253,0.0006991536,0.001805502],"category_scores_gemma":[0.0001560204,0.0002507472,0.0006030003,0.000218075,0.0003947816,0.0004204503,0.00037725,0.001121772,0.0003551368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006896438,"about_ca_system_score_gemma":0.0005452615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002917212,"about_ca_topic_score_gemma":0.005365178,"domain_scores_codex":[0.9997389,0.0000230199,0.00002348615,0.00007030888,0.00009032652,0.00005395259],"domain_scores_gemma":[0.9998626,0.00001677228,0.00004350805,0.00001523784,0.00003058077,0.00003125887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002738106,0.00001760658,0.0001095297,0.00003012425,0.000002718919,0.00001500666,0.000005599675,0.00004919344,0.999266,0.00004831083,0.00003026529,0.0003981911],"study_design_scores_gemma":[0.00004607363,0.002679758,0.009493317,0.00002419067,0.00007826812,0.0002847077,0.00006429435,0.003533866,0.98037,0.0002008611,0.003186336,0.00003819102],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9258612,0.002348177,0.06231173,0.0006790256,0.000265939,0.0005369284,0.002988896,0.0006781578,0.004329938],"genre_scores_gemma":[0.9266872,0.002980808,0.05642719,0.0004391103,0.00004226125,0.001310247,0.002074137,0.00009589751,0.009943024],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002917212,"threshold_uncertainty_score":0.006040037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3263476237829902,"score_gpt":0.4426834446210928,"score_spread":0.1163358208381026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}