{"id":"W2078593189","doi":"10.1310/2xvk-pbgl-735n-wh72","title":"Concomitant Use of an Active Boosted Protease Inhibitor with Enfuvirtide in Treatment-Experienced, HIV-Infected Individuals: Recent Data and Consensus Recommendations","year":2006,"lang":"en","type":"review","venue":"HIV Clinical Trials","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; Maple Leaf Medical Clinic","funders":"","keywords":"Enfuvirtide; Ritonavir; Concomitant; Medicine; Protease inhibitor (pharmacology); Lopinavir; Regimen; Viral load; Pharmacology; Internal medicine; Protease; Virology; Human immunodeficiency virus (HIV); Immunology; Gp41; Antiretroviral therapy; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03511783,0.001413965,0.004544319,0.002713017,0.00166273,0.003794987,0.007160585,0.008396632,0.003004343],"category_scores_gemma":[0.03854967,0.001240701,0.005508603,0.002868865,0.001860185,0.003205138,0.002344244,0.00925835,0.002224484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002360878,"about_ca_system_score_gemma":0.009467993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006483378,"about_ca_topic_score_gemma":0.01316475,"domain_scores_codex":[0.9778264,0.00723403,0.007568749,0.00126265,0.005282926,0.000825349],"domain_scores_gemma":[0.9306256,0.02425473,0.01072327,0.001391139,0.02939943,0.003605834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00116543,0.0006748271,0.005653528,0.04581587,0.002253017,0.0005411434,0.0006325732,0.00119692,0.001353269,0.003271429,0.1891602,0.7482818],"study_design_scores_gemma":[0.002872411,0.001231758,0.01995964,0.132063,0.007495023,0.001523996,0.001676841,0.002024881,0.001869771,0.01005452,0.8189473,0.0002808154],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004419148,0.7265776,0.01225092,0.2266198,0.01333676,0.001740347,0.001228974,0.0004101326,0.01341634],"genre_scores_gemma":[0.03574045,0.7249936,0.1009829,0.1107435,0.01229682,0.004054296,0.004403945,0.0001936213,0.006590705],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03511783,"threshold_uncertainty_score":0.1857231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4705395474442008,"score_gpt":0.5174414029777028,"score_spread":0.04690185553350196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}