{"id":"W2078626574","doi":"10.1039/c3ob40548f","title":"Synthesis and evaluation of an 18F-labelled norbornene derivative for copper-free click chemistry reactions","year":2013,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Tetrazine; Chemistry; Bioconjugation; Click chemistry; Biodistribution; Norbornene; Bioorthogonal chemistry; Combinatorial chemistry; Metabolic stability; Organic chemistry; Biochemistry; In vitro; Polymer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007155089,0.0005565849,0.0003935266,0.0002498911,0.0002156145,0.0003673648,0.0004886795,0.0006550948,0.001290758],"category_scores_gemma":[0.0005701947,0.000256107,0.0003369083,0.0002367962,0.0002910286,0.0004798438,0.0002930338,0.0005411054,0.0004983817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000446665,"about_ca_system_score_gemma":0.000325559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006349128,"about_ca_topic_score_gemma":0.0008187649,"domain_scores_codex":[0.9995778,0.00006775877,0.00003365751,0.00009063182,0.0001763546,0.00005380671],"domain_scores_gemma":[0.999727,0.00004995,0.00005755519,0.00004101681,0.00007356382,0.00005100113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006368411,0.00003623314,0.00004679205,0.00006628779,0.000006563681,0.00009190369,0.00003104418,0.0002247345,0.99732,0.0001753676,0.00002444368,0.001912959],"study_design_scores_gemma":[0.00001825681,0.000396271,0.0002459528,0.000003902009,0.000008727146,0.0001580943,0.000006414676,0.0004897118,0.9971379,0.00001658894,0.001508908,0.00000927204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.968886,0.001452267,0.0256388,0.00007572681,0.00004542384,0.0004531299,0.0002873198,0.0001704448,0.00299105],"genre_scores_gemma":[0.9611602,0.001796475,0.03114234,0.0000344275,0.00001661879,0.0002188311,0.0006616195,0.00007541512,0.00489415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001290758,"threshold_uncertainty_score":0.004318058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01647446809043608,"score_gpt":0.2662970750166231,"score_spread":0.249822606926187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}