{"id":"W2078628885","doi":"10.1038/ncomms5603","title":"DOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCs","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Curtin University of Technology; York University; National Institutes of Health; Children’s Hospital of Wisconsin Research Institute; Seattle Children's Research Institute","keywords":"Innate lymphoid cell; RAR-related orphan receptor gamma; Biology; Citrobacter rodentium; Interleukin 23; Interleukin 22; Innate immune system; Immunity; Cell biology; Orphan receptor; Immunology; Immune system; Interleukin; Interleukin 17; Cytokine; Genetics; FOXP3; Transcription factor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006896061,0.0001222621,0.0002192343,0.00004457927,0.0007802385,0.00001357649,0.0005755181,0.0003933171,0.0000113703],"category_scores_gemma":[0.0005359616,0.00008696635,0.00005547605,0.0001686438,0.0005051334,0.00007389834,0.000220749,0.001157787,0.00001251855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001694183,"about_ca_system_score_gemma":0.00003429678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001749341,"about_ca_topic_score_gemma":0.0004243016,"domain_scores_codex":[0.998562,0.0008965078,0.0002168334,0.0001326485,0.00003480996,0.000157209],"domain_scores_gemma":[0.9974948,0.0009230581,0.0001737561,0.001161588,0.000234691,0.00001213987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004114536,0.0003905716,0.003679963,0.00004087223,0.0005906965,4.743862e-8,0.002193727,0.000009954229,0.8726297,0.1054419,0.006285878,0.00832522],"study_design_scores_gemma":[0.004313111,0.0006093353,0.0753203,0.0001120658,0.0003507469,0.00002328589,0.002377185,0.0002626171,0.07936478,0.01415492,0.8225963,0.0005153763],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8643022,0.09465812,0.004744686,0.006881973,0.001921557,0.002369286,0.002761596,0.0003361451,0.02202442],"genre_scores_gemma":[0.9987118,0.0004797046,0.00009963846,0.0001314259,0.00001838575,0.0000438918,0.0002766608,0.00001033951,0.0002281421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8163104,"threshold_uncertainty_score":0.6001043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01141587305830747,"score_gpt":0.2396663903259856,"score_spread":0.2282505172676781,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}