{"id":"W2078629484","doi":"10.1006/bbrc.2000.3307","title":"Structure-Activity Studies on Mammalian Adenosine Kinase","year":2000,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Heart and Stroke Foundation of Canada","keywords":"Adenosine kinase; Adenosine; Chemistry; Aspartic acid; Binding site; Random coil; Asparagine; Biochemistry; Stereochemistry; Protein secondary structure; Enzyme; Amino acid; Adenosine deaminase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000198907,0.0004093471,0.0004108507,0.0002555613,0.0003427321,0.000484954,0.0007057277,0.0003585103,0.00106729],"category_scores_gemma":[0.000324145,0.0002224021,0.0004537081,0.0004124765,0.0003206283,0.0004645896,0.000150056,0.0007929146,0.0003568807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007441257,"about_ca_system_score_gemma":0.0003587371,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001869716,"about_ca_topic_score_gemma":0.001690368,"domain_scores_codex":[0.9999148,0.00002250974,0.000007707337,0.00001561377,0.0000205413,0.00001889605],"domain_scores_gemma":[0.9998597,0.00005375607,0.00003176758,0.00001278629,0.00001650712,0.00002544411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001791686,0.0002939566,0.001857868,0.0002033806,0.00006154084,0.0004775885,0.0001878696,0.003881079,0.978015,0.004063718,0.0003345983,0.008831546],"study_design_scores_gemma":[0.0001466859,0.001344367,0.009927348,0.00003791618,0.0001300836,0.001389606,0.0001666825,0.01037936,0.9643681,0.001106993,0.01096594,0.00003688132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889154,0.005260127,0.002009788,0.0002720431,0.00003338775,0.00002413364,0.0002910406,0.00003304371,0.003161174],"genre_scores_gemma":[0.9904279,0.003773215,0.002070563,0.00008735244,0.00002665822,0.00001972254,0.001397695,0.00001270875,0.002184207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001869716,"threshold_uncertainty_score":0.005398989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09276366039199196,"score_gpt":0.4122318325209729,"score_spread":0.3194681721289809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}