{"id":"W2078641664","doi":"10.1042/bj20090907","title":"Identification of the key structural motifs involved in HspB8/HspB6–Bag3 interaction","year":2009,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; Hôtel-Dieu de Québec","funders":"Hsinchu Science Park Bureau, Ministry of Science and Technology, Taiwan; Cambridge Institute for Medical Research, University of Cambridge; Canadian Institutes of Health Research","keywords":"BAG3; WW domain; Co-chaperone; Chaperone (clinical); Biology; Heat shock protein; Cell biology; Mutant; Protein folding; HEK 293 cells; Protein–protein interaction; Genetics; Hsp70; Gene; Autophagy; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003234753,0.00009722702,0.0001055455,0.00006393645,0.00006037843,0.000036236,0.0003508358,0.0001493062,0.00001865232],"category_scores_gemma":[0.0004044168,0.00007082954,0.0001056748,0.000160958,0.00007023726,0.000009284329,0.00007701384,0.0003487489,0.000003368965],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006672856,"about_ca_system_score_gemma":0.0001013507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000073866,"about_ca_topic_score_gemma":0.000006259281,"domain_scores_codex":[0.9988407,0.0001155359,0.0004009682,0.0001781498,0.0002651399,0.000199428],"domain_scores_gemma":[0.99937,0.000008756885,0.0001353575,0.0002654399,0.0001401822,0.00008030852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008553549,0.0000367542,0.002476083,0.000005946445,0.000009251468,0.000001529752,0.00003349901,0.00002568458,0.9948187,0.00001932877,0.0005137059,0.001973971],"study_design_scores_gemma":[0.0003458428,0.00007981883,0.02474915,0.00002955517,0.000003775779,0.00006227638,0.00004860095,0.0002472513,0.9736418,0.0003782899,0.0003381678,0.00007548819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983521,0.0002821444,0.0002130808,0.0007706244,0.0001405085,0.0001407713,0.000003917999,0.000002927801,0.00009391659],"genre_scores_gemma":[0.9993879,0.00004087185,0.0001453342,0.00008490673,0.0002423321,0.000002842162,0.00001089066,0.000007472678,0.0000774983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02227307,"threshold_uncertainty_score":0.2888345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01523650418827345,"score_gpt":0.3073152088612444,"score_spread":0.2920787046729709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}