{"id":"W2078660705","doi":"10.1016/j.pharmthera.2005.06.012","title":"Involving the pharmaceutical and biotech communities in medication development for substance abuse","year":2005,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nalcor Energy (Canada)","funders":"","keywords":"Legislation; General partnership; Substance abuse; Drug development; Business; Pharmaceutical industry; Medicine; Clinical trial; Marketing; Public relations; Risk analysis (engineering); Drug; Pharmacology; Psychiatry; Finance; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01230203,0.001272996,0.00285531,0.004489365,0.0004130361,0.002174155,0.001428339,0.002643781,0.002745659],"category_scores_gemma":[0.01612903,0.0006185836,0.0009832761,0.006347117,0.002261794,0.002904635,0.001120512,0.003517224,0.00143742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001339472,"about_ca_system_score_gemma":0.005074299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001959187,"about_ca_topic_score_gemma":0.00444941,"domain_scores_codex":[0.9954426,0.00257758,0.0004300328,0.0002475102,0.001217412,0.00008479513],"domain_scores_gemma":[0.9625728,0.0330735,0.00175021,0.0004684203,0.001799131,0.0003359223],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006020669,0.00007135337,0.0002446977,0.0162912,0.0002370447,0.00008607499,0.00008283958,0.001031003,0.0003650144,0.01842301,0.01201266,0.9510949],"study_design_scores_gemma":[0.0002267333,0.0004178034,0.002783062,0.02362492,0.000631589,0.002303232,0.0002806538,0.002030395,0.001555524,0.08766305,0.8783641,0.0001189873],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001306967,0.9923992,0.004949133,0.001283236,0.0002327404,0.00001634164,0.000009783105,0.00001856805,0.0009603226],"genre_scores_gemma":[0.002217864,0.990209,0.005960822,0.0006346405,0.0004830624,0.00003130314,0.0000177019,0.000007288808,0.0004383214],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01230203,"threshold_uncertainty_score":0.06506014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7951575327030591,"score_gpt":0.6443657248602361,"score_spread":0.150791807842823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}