{"id":"W2078660705","doi":"10.1016/j.pharmthera.2005.06.012","title":"Involving the pharmaceutical and biotech communities in medication development for substance abuse","year":2005,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Statistical Methods in Clinical Trials","field":"Mathematics","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nalcor Energy (Canada)","funders":"","keywords":"Legislation; General partnership; Substance abuse; Drug development; Business; Pharmaceutical industry; Medicine; Clinical trial; Marketing; Public relations; Risk analysis (engineering); Drug; Pharmacology; Psychiatry; Finance; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006596103,0.0005072005,0.001793383,0.000170935,0.0002503245,0.00004025221,0.0007840065,0.0006278292,0.0001906088],"category_scores_gemma":[0.000503129,0.0003480162,0.0001856156,0.0002735025,0.0007736392,0.00004892729,0.00009612426,0.001508489,0.00001043458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650221,"about_ca_system_score_gemma":0.0002529965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001780468,"about_ca_topic_score_gemma":0.00004139902,"domain_scores_codex":[0.99422,0.002812427,0.001768017,0.0003934557,0.0002398191,0.0005663295],"domain_scores_gemma":[0.9066846,0.09216198,0.0005987743,0.0003491406,0.00009651841,0.0001090242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004924323,0.0002106813,0.000003904638,0.003731898,0.0006400898,0.000001580419,0.00198456,1.554388e-7,0.000005198373,0.002677497,0.0002987208,0.9903965],"study_design_scores_gemma":[0.001051269,0.00003465814,0.000001489167,0.001276712,0.002971007,0.00001255158,0.0001272127,0.000348175,0.00004844553,0.02092114,0.9728521,0.0003552562],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009258556,0.9814957,0.01369946,0.000768112,0.0009001555,0.002858695,0.00006825889,0.00008149709,0.00003553735],"genre_scores_gemma":[0.000009982662,0.837122,0.1590612,0.002248374,0.0003942178,0.00103105,0.00001608447,0.00008367959,0.00003350727],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9900412,"threshold_uncertainty_score":0.9998972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.7951575327030591,"score_gpt":0.6443657248602361,"score_spread":0.150791807842823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}