{"id":"W2078715563","doi":"10.1074/jbc.m302675200","title":"Grb2-independent Recruitment of Gab1 Requires the C-terminal Lobe and Structural Integrity of the Met Receptor Kinase Domain","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"GRB2; Signal transducing adaptor protein; Cell biology; Receptor tyrosine kinase; Biology; Hepatocyte Growth Factor Receptor; Tyrosine kinase; Cancer research; Signal transduction; Chemistry; Receptor; Biochemistry; Hepatocyte growth factor; C-Met","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001181452,0.0003169142,0.0001240296,0.0001228501,0.0001654981,0.0003181688,0.0001801241,0.0001839062,0.001472105],"category_scores_gemma":[0.000134636,0.0001349058,0.00013504,0.0001057205,0.0001872492,0.0001784706,0.00030099,0.0003661383,0.0007206591],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005089765,"about_ca_system_score_gemma":0.0003685623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001256719,"about_ca_topic_score_gemma":0.003178468,"domain_scores_codex":[0.9999188,0.00001324408,0.000006809361,0.00001462381,0.00002364296,0.00002291802],"domain_scores_gemma":[0.9999355,0.00000750355,0.00001365496,0.000007612727,0.000007893164,0.00002777133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009755002,0.00001289715,0.0002204673,0.00003061403,0.000003031853,0.00007828114,0.000007038936,0.00008264574,0.99831,0.0003048591,0.00004579535,0.0008067599],"study_design_scores_gemma":[0.00004529825,0.00005811382,0.01078962,0.000007392488,0.000008738002,0.0006738882,0.00002693677,0.003327331,0.977687,0.0001758038,0.007194444,0.000005451497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923511,0.001179723,0.003128732,0.0001487648,0.00002249284,0.00001985823,0.0003523708,0.00007801377,0.002718902],"genre_scores_gemma":[0.9904046,0.0004971034,0.002968109,0.00004998957,0.00000548563,0.00002307168,0.001028901,0.0000272441,0.004995555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001472105,"threshold_uncertainty_score":0.004924715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03611262313887151,"score_gpt":0.2899220973898198,"score_spread":0.2538094742509483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}