{"id":"W2078804817","doi":"10.1212/wnl.0000000000000137","title":"Pregnancy outcomes in the clinical development program of fingolimod in multiple sclerosis","year":2014,"lang":"en","type":"article","venue":"Neurology","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Teva Pharmaceutical Industries; Eli Lilly and Company","keywords":"Fingolimod; Medicine; Pregnancy; In utero; Obstetrics; Clinical trial; Pediatrics; Live birth; Fetus; Multiple sclerosis; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005367582,0.00009709515,0.0002241783,0.00004826978,0.00002198305,0.000005064486,0.000258937,0.0001527549,0.00000251201],"category_scores_gemma":[0.0004127248,0.00007072517,0.00006237078,0.00008105479,0.00007470869,0.000001829077,0.00008126985,0.0001548408,0.00000228956],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000117832,"about_ca_system_score_gemma":0.00003412925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000395379,"about_ca_topic_score_gemma":0.0003616963,"domain_scores_codex":[0.9987416,0.0003063225,0.0003996071,0.000258838,0.00007830764,0.0002152732],"domain_scores_gemma":[0.9994829,0.0001239819,0.00008471074,0.0002649849,0.0000198119,0.00002359065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009040558,0.0004759415,0.9345721,0.00001238114,0.00001016063,0.000001859021,0.0002006766,0.00006215714,0.01522731,0.00007948776,0.00001808625,0.04924946],"study_design_scores_gemma":[0.001283368,0.0004827736,0.9829563,0.00001168245,0.000004299682,0.000001816096,0.000007995221,0.0001425595,0.006945706,0.00003152086,0.008052932,0.00007902474],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989746,0.0001691127,0.00009714236,0.0001843718,0.0001611536,0.0002457428,9.48773e-7,0.00000605696,0.0001609189],"genre_scores_gemma":[0.998044,0.00005383032,0.0008814047,0.0008858144,0.00005461925,0.00005467363,0.000009097851,0.000009454136,0.00000710935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04917044,"threshold_uncertainty_score":0.2884089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05901843296169224,"score_gpt":0.3038637496285074,"score_spread":0.2448453166668151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}