{"id":"W2078823122","doi":"10.1016/j.pbi.2007.07.010","title":"Ubiquitin ligases mediate growth and development by promoting protein death","year":2007,"lang":"en","type":"review","venue":"Current Opinion in Plant Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":168,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; National Science Foundation","keywords":"Biology; Ubiquitin; Proteasome; Cell biology; Transcription factor; Hormone; Signal transduction; Adaptation (eye); Protein degradation; Ubiquitin ligase; Biochemistry; Neuroscience; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008520106,0.0005535083,0.000916362,0.0002123785,0.00008802098,0.00002612767,0.0003226199,0.000703197,0.00001067139],"category_scores_gemma":[0.0001942824,0.000458571,0.000110799,0.00009934598,0.0001013517,0.000003710752,0.0003404818,0.0004830681,0.00001644288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003564354,"about_ca_system_score_gemma":0.0003449034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007078875,"about_ca_topic_score_gemma":0.000003817214,"domain_scores_codex":[0.9970912,0.0004142131,0.0009021262,0.0008710528,0.0001095684,0.0006117977],"domain_scores_gemma":[0.9990616,0.0000842113,0.0004247638,0.0002246412,0.00003077461,0.0001739757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002435672,0.000130056,0.0002919399,0.01590232,0.00006483081,0.000002579394,0.00006133031,9.988908e-9,0.00125339,0.0002641987,0.0007755268,0.9812295],"study_design_scores_gemma":[0.0002899241,0.0001836834,0.000004543388,0.00753752,0.0000152253,0.00007016038,0.000006194206,8.167436e-7,0.007435115,0.00002812845,0.9838976,0.0005311299],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008226727,0.9958124,0.0001454861,0.00001125554,0.001035544,0.001406951,0.0006513656,0.00002617584,0.00008812533],"genre_scores_gemma":[0.0001847324,0.9858259,0.0002868774,0.0000140442,0.0006153859,0.0005187358,0.01249113,0.00004537587,0.00001781681],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9831221,"threshold_uncertainty_score":0.9997866,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09934310981460256,"score_gpt":0.3601089575247034,"score_spread":0.2607658477101008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}